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Toralactone 目录号 GC61338

Toralactone可从Cassiaobtusifolia中分离得到,通过Nrf2依赖的抗氧化机制介导肝保护。

规格 价格 库存 购买数量
1mg
¥1,170.00
现货

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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. 41743-74-2 SDF Download SDF
别名 N/A
化学名 N/A
Canonical SMILES O=C1C2=C(O)C3=C(O)C=C(OC)C=C3C=C2C=C(C)O1
分子式 C15H12O5 分子量 272.25
溶解度 N/A 储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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产品描述

Toralactone, isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism[1].

Toralactone sensitize resistant MCF-7adr cell line to paclitaxel via inhibiting P-glycoprotein efflux activity[2].

[1]. YongtaekSeo, et al. Toralactone glycoside in Cassia obtusifolia mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism. Food Research International. Volume 97, July 2017, Pages 340-346. [2]. Salwa D. Alqahtani, et al. Abstract 1205: Rubrofusarin and toralactone sensitize resistant MCF-7adr cell line to paclitaxel via inhibiting P-glycoprotein efflux activity. AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC.