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Sincalide

目录号 : GP21306

Sincalide (Cholecystokinin octapeptide, CCK-8) 是一种快速作用的胆囊收缩素 (CCK) 氨基酸多肽激素类似物,可用于静脉输液后胆囊造影。

Sincalide Chemical Structure

规格 价格 库存 购买数量
1mg
¥840.00
5-10工作日
5mg
¥2,030.00
5-10工作日
25mg
¥7,000.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

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产品描述

Sincalide also called CCK-8 has a molecular formula of C49H62N10O16S3 , H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2 having an Mw of 1143.27 Dalton.

Product Data

Purity Greater than 99.0% as determined by RP-HPLC. Source
Phycical Appearance Sterile Filtered White lyophilized (freeze-dried) powder. Shipping Condition Shipped at Room temp.
Solubility It is recommended to reconstitute the lyophilized Sincalide in sterile 18MΩ-cm H2O at a concentration of 0.5mg/ml, which can then be further diluted to other aqueous solutions.
Stability Lyophilized Sincalide although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution CCK-8 should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Formulation The Sincalide was lyophilized from a concentrated (1mg/ml) solution with no additives.

Introduction

Sincalide corresponds to the C-terminal octapeptide of cholecystokinin (CCK) which acts on receptors within the gallbladder wall causing it to contract.Cholecystokinin (CCK) is a hormone originally isolated from porcine intestinal mucosa and described as a linear 33-amino acid peptide containing a sulfated tyrosine, which is essential for its biological activity. It has been found in mammals in both the digestive tract and the central nervous system. Among its multiple biological functions, this hormone stimulates pancreatic exocrine secretion, gallbladder contraction, and intestine motility and may also act as a neurotransmitter/neuromodulator in the central nervous system.

Stability

Lyophilized Sincalide although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution CCK-8 should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.