SERPINE2 Mouse
目录号 : GP22246Plasminogen Activator Inhibitor-2 Mouse Recombinant
Sample solution is provided at 25 µL, 10mM.
SERPINE2 produced in Sf9 Baculovirus cells is a single,glycosylated polypeptide chain containing 386 amino acids (20-397a.a.) andhaving a molecular mass of 42.9kDa (Molecular size on SDS-PAGE will appear atapproximately 40-57kDa).SERPINE2 is expressed with a 8 amino acid His tag atC-Terminus and purified by proprietary chromatographic techniques.
Purity | Greaterthan 95.0% as determined by SDS-PAGE. | Source | Sf9, Baculovirus cells. |
Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | Serpnie2; B230326M24Rik; PAI-1; PI-7; PI7; PN-1; Spi4; Glia-derivednexin; GDN;Peptidase inhibitor 7; Protease nexin 1; Protease nexin I; Serineprotease-inhibitor 4; Serpin E2. | ||
Amino Acid Sequence | SQFNSLSLEE LGSNTGIQVF NQIIKSRPHE NVVVSPHGIA SILGMLQLGADGKTKKQLST VMRYNVNGVG KVLKKINKAI VSKKNKDIVT VANAVFLRNG FKMEVPFAVR NKDVFQCEVQNVNFQDPASA SESINFWVKN ETRGMIDNLL SPNLIDGALT RLVLVNAVYF KGLWKSRFQP ESTKKRTFVAGDGKSYQVPM LAQLSVFRSG STRTPNGLWY NFIELPYHGE SISMLIALPT ESSTPLSAII PHITTKTIDSWMNTMVPKRM QLVLPKFTAV AQTDLKEPLK ALGITEMFEP SKANFTKITR SESLHVSHIL QKAKIEVSEDGTKASAATTA ILIARSSPPW FIVDRPFLFS IRHNPTGAIL FLGQVNKPLE HHHHHH. | ||
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
Formulation | SERPINE2 protein solution (0.5mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 10% glycerol. |
PlasminogenActivator Inhibitor-2 (Serpine2) which inhibits thrombin, plasmin andplasminogen activators is a part of the Serpin superfamily of the serineprotease inhibitors. Serpine2 is able to transform human embryonic kidney cellsinto neuron-like cells. Furthermore, Serpine2's over expression in mice leadsto progressive neuronal and motor dysfunction.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.