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sCD23 Human

目录号 : GP23021

Soluble CD23 Human Recombinant

sCD23 Human Chemical Structure

规格 价格 库存 购买数量
5μg
¥840.00
5-10工作日
20μg
¥2,030.00
5-10工作日
1mg
¥37,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

sCD23 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 172 amino acids and having a molecular mass of 19.2kDa.

Product Data

Purity Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile Filtered White lyophilized (freeze-dried) powder. Shipping Condition Shipped at Room temp.
Synonyms Low affinity immunoglobulin epsilon Fc receptor; Lymphocyte IgE receptor; Fc-epsilon-RII; BLAST-2; Immunoglobulin E-binding factor; CD23 antigen; FCER2; CD23; FCE2; CD23A; IGEBF; CLEC4J.
Amino Acid Sequence MELQVSSGFV CNTCPEKWIN FQRKCYYFGK GTKQWVHARY ACDDMEGQLV SIHSPEEQDF LTKHASHTGS WIGLRNLDLK GEFIWVDGSH VDYSNWAPGE PTSRSQGEDC VMMRGSGRWN DAFCDRKLGA WVCDRLATCT PPASEGSAES MGPDSRPDPD GRLPTPSAPL HS
Solubility It is recommended to reconstitute the lyophilized sCD23 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability Lyophilized sCD23 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution sCD23 should be stored at 4°C between 2-7 days and for future use below -18°C . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Biological Activity The ED50 is determined by its ability to induce TNF-alpha production by human PBMCs.
Formulation Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

Introduction

CD23 is a 45kDa glycoprotein, which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma.

Biological Activity

The ED50 is determined by its ability to induce TNF-alpha production by human PBMCs.

Stability

Lyophilized sCD23 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution sCD23 should be stored at 4°C between 2-7 days and for future use below -18°C . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.