SAE1/SAE2 Human
目录号 : GP26180SAE1/SAE2 Human Recombinant produced in SF9 is glycosylated, polypeptide chain containing 2 subunits (SAE1 subunit molecular mass is 39kDa & SAE2 subunit molecular mass is 73kDa)
Sample solution is provided at 25 µL, 10mM.
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SAE1/SAE2 Human Recombinant produced in SF9 is glycosylated, polypeptide chain containing 2 subunits (SAE1 subunit molecular mass is 39kDa & SAE2 subunit molecular mass is 73kDa). The subunits associate to form a complex.The SAE1/SAE2 is expressed with a -10xHis tag and purified by proprietary chromatographic techniques.
| Purity | Greater than 80.0% as determined by SDS-PAGE. | Source | Sf9 insect cells. |
| Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | withIcePacks |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. | ||
| Formulation | SAE1/SAE2 is supplied in 20mM HEPES buffer pH-7.5, 400mM NaCl and 20% glycerol. | ||
SAE1 and SAE2 form heterodimers which take part in the posttranslational modification of proteins (sumoylation). This process regulates protein structure as well as intracellular localization of the target. SAE1/SAE2 may indicate on dermatomyositis (DM) as autoantibodies against those 2 proteins have been found in patients.
Western blot with anti SAE1/SAE2 autoantibody positive sample & Polyclonal anti-SAE1 and anti-SAE2 antibodies.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.