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Home >> Signaling Pathways >> Microbiology & Virology >> Bacterial

Bacterial(细菌)

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Products for  Bacterial

  1. Cat.No. 产品名称 Information
  2. GC18670 Cefuroxime

    头孢呋辛是一种具有口服活性的第二代头孢菌素抗生素，对 β-内酰胺酶具有更高的稳定性。
  3. GC60374 Trovafloxacin A topoisomerase IV and DNA gyrase inhibitor
  4. GC60347 Sulfadiazine sodium A sulfonamide antibiotic
  5. GC60340 Skullcapflavone II SkullcapflavoneII是从黄芩中提取的黄酮类化合物，具有抗炎、抗菌作用。SkullcapflavoneII调节破骨细胞的分化、存活和功能。SkullcapflavoneII对M.aurum和M.bovisBCG具有较强的抗菌活性。
  6. GC60314 Pyraclostrobin Pyraclostrobin 是一种球果苷杀菌剂 (fungicide)，可抑制真菌和哺乳动物细胞的线粒体复合物 III (mitochondrial complex III)。Pyraclostrobin 可诱导 3T3-L1 细胞内甘油三酯的积累。
  7. GC60310 Psammaplin A PsammaplinA是一种海洋代谢产物，是HDAC和DNA甲基转移酶(DNAmethyltransferases)的有效抑制剂。PsammaplinA是一种高效的选择性HDAC1抑制剂，IC50为0.9nM，对HDAC1的选择性是DAC6的360倍，对HDAC7和HDAC8的效力低1000倍以上。PsammaplinA对革兰氏阳性细菌(Gram-positivebacteria)具有抗菌作用，并抑制DNA合成和DNA促旋酶(DNAgyrase)活性。抗肿瘤活性。
  8. GC60302 Primin A benzoquinone with diverse biological activities
  9. GC60277 Ombuoside Ombuoside是从绞股蓝(Gynostemmapentaphyllum)分离得到的糖苷复合物。Ombuoside具有抗微生物活性，对几种革兰氏阳性菌和革兰氏阴性菌以及白色念珠菌(Candidaalbicans)有抑制作用。Ombuoside具有清除自由基和ROS抗氧化作用。
  10. GC60276 Ombuin Ombuin 是从花椒中分离出的，具有广谱抗菌作用，MIC 为 125 至 500 μg/mL。
  11. GC60273 NSC-60339 NSC-60339 是外排泵的抑制剂和 AcrAB-TolC 的底物，是聚对苯二甲酸衍生物，是一种潜在的癌症化疗化合物。
  12. GC60221 Lactoferrin (17-41) (acetate) Lactoferrin 17-41 (Lactoferricin B) acetate 对应于牛乳铁蛋白的残基 17-41，对革兰氏阳性和革兰氏阴性细菌、病毒、原生动物和真菌等多种微生物具有抗菌活性。Lactoferrin 17-41 acetate 具有抗肿瘤活性。
  13. GC60206 Isoastilbin Isoastilbin，RhizomaSmilacisglabrae和Astragalusmembranaceus中的一种二氢黄酮醇糖苷化合物。Isoastilbin抑制葡萄糖基转移酶(GTase)的IC50值为54.3μg/mL，还抑制酪氨酸酶(tyrosinase)活性。Isoastilbin具有神经保护，抗氧化，抗微生物和抗凋亡的特性，并可用于阿尔茨海默氏病的研究。
  14. GC60189 Hesperetin 7-O-glucoside A flavanone glucoside with diverse biological activities
  15. GC60185 Hamamelitannin Hamamelitannin 是从 Hamamelis virginiana 树皮中提取的多酚，是一种群体感应 (QS) 抑制剂。Hamamelitannin 通过影响肽聚糖生物合成和 eDNA 释放增加金黄色葡萄球菌生物膜的抗生素敏感性。
  16. GC60174 Ginsenoside Rg4 GinsenosideRg4是一种从PanaxginsengC.A.Meyer的叶子中分离出来的一种主要的人参三醇型人参皂苷。人参三醇型人参皂苷(如GinsenosideRg4)具有多种生物活性，包括防腐，抗糖尿病，伤口愈合，免疫刺激和抗氧化活性。
  17. GC60138 DIMBOA

    DIMBOA (2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one) is a benzoxazinoid (BX), is a secondary metabolite in grasses .
  18. GC60136 Dicresulene diammonium Dicresulenediamiumium是一种Policresulen的杂质，Policresulen是一种具有止血，抗菌和抗病毒活性的有机酸。
  19. GC60131 Dermaseptin TFA Dermaseptin TFA 是从青蛙皮肤中分离出来的一种肽，在微摩尔浓度下表现出对细菌、真菌和原生动物强有力的抗菌 (antimicrobial) 活性。
  20. GC60125 D-Cysteine D-Cysteine 是半胱氨酸的 D 型异构体，也是一种大肠杆菌生长的有力抑制剂。D-Cysteine 由 D-氨基酸氧化酶介导产生 H2S，并且是针对小脑共济失调的神经保护剂。D-Cysteine 可抑制由变形链球菌和血红链球菌形成的双物种生物膜的生长和致龋性。
  21. GC60105 Cefquinome sulfate A broad-spectrum cephalosporin antibiotic
  22. GC60104 Cefodizime sodium Cefodizime Sodium, a third generation cephalosporin antibiotic, has broad-spectrum activity and is stable to most beta-lactamases.
  23. GC60039 ACHN-975 TFA ACHN-975 是细菌酶 LpxC 的选择性抑制剂，表现出亚纳摩尔级 LpxC 抑制活性。ACHN-975 对多种革兰氏阴性菌的 MIC 值低于 1 μg/mL。
  24. GC60036 9-Hydroxycalabaxanthone 9-Hydroxycalabaxanthone(XanthoneI)是一种黄酮类物质，从Garciniamangostana中分离得到的。9-Hydroxycalabaxanthone具有群体感抑菌、抗菌和抗疟活性(IC50=1.2-1.5µM)。
  25. GC60031 6-Azathymine 6-Azathymine，胸腺嘧啶的6-氮类似物，是一种有效的D-3-氨基异丁酸酯-丙酮酸氨基转移酶(D-3-aminoisobutyrate-pyruvateaminotransferase)抑制剂。6-Azathymine可抑制DNA的生物合成，并具有抗菌和抗病毒活性。
  26. GC60011 1,3-Dithiane 1,3-二噻烷2位的亚甲基氢具有较高的酸度（pKa31.1），在烷基锂等强碱作用下可生成烷基阴离子物种。由于硫缩醛通过脱保护转化为羰基，1,3-二噻烷可用作酰基阴离子等价物（酰基极性改变）。也就是说，酮醛可以通过使亲核试剂如卤代烷反应然后将产物水解来获得。它也可以通过脱硫反应转化为烷烃。
  27. GC39839 S.pombe lumazine synthase-IN-1 S.pombe lumazine synthase-IN-1 是 lumazine 合酶的抑制剂，对粟酒裂殖酵母和结核分枝杆菌的 lumazine 合酶的 Ki 值分别为 243 μM 和 9.6 μM。
  28. GC39822 Thiacetazone An antitubercular agent
  29. GC39792 Halazone Halazone (Pantocide, p-sulfondichloramidobenzoic acid) is widely used to disinfect drinking water.
  30. GC39782 6-Aminopenicillanic acid An intermediate in the semisynthetic synthesis of penicillin antibiotics
  31. GC39742 Potassium guaiacolsulfonate hemihydrate Potassium guaiacolsulfonate hemihydrate (Potassium Hydroxymethoxybenzenesulfonate, Sulfogaiacol) is used as an expectorant for relieving symptoms of cough and mucus in the chest due to respiratory infections, asthma, colds, or hay fever.
  32. GC39719 Nigericin

    A potassium ionophore
  33. GC39662 Erythromycin estolate Erythromycin (Lubomycine B), a naturally occurring macrolide, is derived from Streptomyces erythrus. It inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.
  34. GC39661 Chloramphenicol succinate sodium A prodrug form of chloramphenicol
  35. GC39660 Metronidazole Benzoate An antibiotic and antiprotozoal agent
  36. GC39655 ABMA ABMA 是一种细胞内毒素和病原体的广谱抑制剂。ABMA 有效地保护细胞免受各种毒素和病原体的侵害，包括病毒，细胞内细菌和寄生虫。ABMA 选择性作用于宿主细胞晚期内体，而不是针对毒素或病原体本身，具有广谱抗感染活性。
  37. GC39633 LtaS-IN-1 LtaS-IN-1 (compound 1771) 是一种高效的小分子脂磷壁酸 (LTA) 抑制剂，可抑制耐多药 (MDR) 大肠杆菌中脂磷壁酸 (LTA) 的合成，并可改变细胞壁的形态。LtaS-IN-1 单独使用抑制肠球菌的生长的 MIC 值范围从 0.5 μg/mL 到 64 μg/mL。LtaS-IN-1 与抗生素联合使用几乎可以完全抑制耐多药的大肠杆菌生长。
  38. GC39602 Cefcapene pivoxil hydrochloride hydrate Cefcapene Pivoxil is the pivalate ester prodrug form of cefcapene, a semi-synthetic third-generation cephalosporin with antibacterial activity.
  39. GC39580 Ceftezole sodium Ceftezole Sodium (Celoslin sodium, Falomesin sodium) is the sodium salt form of ceftezole, a semi-synthetic first-generation cephalosporin with antibacterial activity.
  40. GC39579 Sulbenicillin disodium Sulbenicillin Sodium (Sulfocillin, Sulfobenzylpenicillin) is the sodium salt of sulbenicillin, which is a penicillin antibiotic.
  41. GC39569 G907 G907 是 ABC transporter, MsbA 的选择性小分子拮抗剂。 G907 抑制两栖动物中纯化的大肠杆菌 MsbA (IC50=18 nM)。G907 通过楔入结构上保守的跨膜袋，使 MsbA 陷入向内的脂多糖结合构象中。G907 具有杀菌活性。
  42. GC39548 Cefuroxime axetil Cefuroxime axetil, a prodrug of the cephalosporin cefuroxime, is a second generation oral cephalosporin antibiotic with in vitro antibacterial activity against several gram-positive and gram-negative organisms.
  43. GC39545 Penicillin G benzathine tetrahydrate Penicillin G benzathine tetrahydrate (Benzathine benzylpenicillin tetrahydrate) 是一种能抗多种细菌感染的抗生素。
  44. GC39544 Sultamicillin tosylate Sultamicillin Tosylate is the tosylate salt of the double ester of sulbactam plus ampicillin. Sulbactam is a semisynthetic beta-lactamase inhibitor which, in combination with ampicillin, extends the antibacterial activity of the latter to include some beta-lactamase-producing strains of bacteria that would otherwise be resistant.
  45. GC39543 Penicillin G Procaine Procaine benzylpenicillin (Procaine benzylpenicillin,PGP), also known as Procaine benzylpenicillin, is an antibiotic useful for the treatment of a number of bacterial infections.
  46. GC39542 Cefazedone Cefazedone (Refosporen, Cefazedonum) is a semisynthetic first-generation cephalosporin with antibacterial activity.
  47. GC39538 Meclocycline Sulfosalicylate Salt Meclocycline Sulfosalicylate Salt 是一种具有广谱抗菌活性的四环素抗生素，可预防皮肤细菌感染，例如寻常痤疮。
  48. GC39537 Cefodizime Cefodizime (CEF, CDZ) is an aminothiazolyl cephalosporin with a broad spectrum of antibacterial activity.
  49. GC39505 Saccharin Saccharin (Benzoic sulfimide, O-Sulfobenzimide, O-Benzoic sulfimide, Saccharimide) is an artificial sweetener with effectively no food energy.
  50. GC39448 Surfactin C1 A lipopeptide biosurfactant
  51. GC39429 Rabeprazole Sulfide An active metabolite of rabeprazole

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