ROCK(Rho相关蛋白激酶)
ROCK (Rho-associated protein kinase) is a kinase belonging to the AGC family of serine-threonine kinases and takes part in regulating the shape and movement of cells by acting on the cytoskeleton.
- Cat.No. 产品名称 Information
-
GC25482
GSK269962A HCl
GSK269962A HCl (GSK269962B, GSK269962) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
-
GC66338
ROCK1-IN-1
WAY-624704 is a novel Rho kinases (ROCK) inhibitor with an Ki of 17 nM.
-
GC66050
Rho-Kinase-IN-2
-
GC63716
Sovesudil hydrochloride
-
GC63351
Sovesudil
-
GC63333
Cotosudil
-
GC63253
Verosudil
-
GC49334
Chroman 1 (hydrochloride hydrate)
A ROCK2 inhibitor
-
GC50116
OXA 06 dihydrochloride
Potent ROCK inhibitor
-
GC50092
RKI 1447 dihydrochloride
A ROCK1 and ROCK2 inhibitor
-
GC50043
SR 3677 dihydrochloride
A ROCK1 and ROCK2 inhibitor
-
GC38898
CCG-222740
CCG-222740 is a Rho/MRTF pathway inhibitor. CCG-222740 decreases the activation of stellate cells in vitro and in vivo, by reducing the levels of alpha smooth muscle actin(α-SMA) expression.
-
GC38791
GSK-25
-
GC37947
Y-33075
An inhibitor of ROCK2
-
GC37551
ROCK inhibitor-2
-
GC37534
Ripasudil free base
-
GC36208
H-1152 dihydrochloride
H-1152 dihydrochloride (2HCl) is a membrane-permeable and selective inhibitor of Rho-associated protein kinase (ROCK). H-1152 inhibits ROCK2, PKA, PKC, PKG, AuroraA and CaMK2 with IC50 of 0.0120 μM, 3.03 μM, 5.68 μM, 0.360 μM, 0.745 μM and 0.180 μM, respectively.
-
GC36207
H-1152
A ROCK inhibitor
-
GC35442
Azaindole 1
A ROCK1 and ROCK2 inhibitor
-
GC43286
CMPD101
A GRK2 and GRK3 inhibitor
-
GC42747
Afuresertib (hydrochloride)
A pan-Akt inhibitor
-
GC41737
(S)-Glycyl-H-1152 (hydrochloride)
A ROCK inhibitor
-
GC34300
AR-13324 analog mesylate
-
GC33901
Pentanoic acid
Pentanoicacid是一种短链脂肪酸,是细菌代谢产物,与过敏性皮肤病有关系。Pentanoicacid能够激活ROCK信号通路。
-
GC33310
Rho-Kinase-IN-1
-
GC33120
ZINC00881524
A ROCK inhibitor
-
GC32868
BDP5290
BDP5290 is a potent inhibitor of ROCK and MRCK with IC50 values of 17nM, 230nM, 123nM and 100nM for MRCKβ, ROCK1, ROCK2, respectively .
-
GC31952
ROCK-IN-1
-
GC31883
ROCK2-IN-2
-
GC19177
GSK180736A
A ROCK1 and GRK2 inhibitor
-
GC19034
AR-13324 mesylate
AR-13324 是一种有效的 ROCK I 和 ROCK II 抑制剂,已被证明可在低浓度下诱导培养的人和猪 TM 细胞的形态学变化。
-
GC10716
Netarsudil (AR-13324)
ROCK抑制剂
-
GC12402
LX7101 HCL
A LIMK and ROCK inhibitor
-
GC13759
SAR407899
A ROCK1 and ROCK2 inhibitor
-
GC16289
SAR407899 hydrochloride
A ROCK1 and ROCK2 inhibitor
-
GC16475
Afuresertib
A pan-Akt inhibitor
-
GC12817
K–115 hydrochloride dihydrate
K-115 hydrochloride dihydrate (K-115) 是 ROCK 的特异性抑制剂,对 ROCK2 和 ROCK1 的 IC50 分别为 19 和 51 nM。
-
GC15170
SB 772077B dihydrochloride
A ROCK1 and ROCK2 inhibitor
-
GC17712
AT13148
A multi-AGC kinase inhibitor
-
GC13869
Fasudil
Fasudil (HA-1077; AT877) 是一种非特异性 RhoA/ROCK 抑制剂,对蛋白激酶也有抑制作用,对 ROCK1 的 Ki 为 0.33 μM,对 ROCK2 和 PKA 的 IC50 分别为 0.158 μM 和 4.58 μM、12.30 μM、1.650 μM ,PKC,PKG,分别。 Fasudil 也是一种有效的 Ca2+ 通道拮抗剂和血管扩张剂。
-
GC17936
GSK269962A
A ROCK1 and ROCK2 inhibitor
-
GC10722
SR-3677
A ROCK1 and ROCK2 inhibitor
-
GC15712
Y-27632
A ROCK inhibitor
-
GC13423
Y-39983 dihydrochloride
ROCK family inhibitor
-
GC14289
Fasudil (HA-1077) HCl
Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μ ;M, 1.650 μM 分别代表 ROCK2 和 PKA、PKC、PKG。 Fasudil (HA-1077) HCl 也是一种有效的 Ca2+ 通道拮抗剂和血管扩张剂。
-
GC18119
GSK429286A
A ROCK inhibitor
-
GC11181
Thiazovivin
A ROCK inhibitor
-
GC12827
SLx-2119
A ROCK2 inhibitor
-
GC15437
RKI-1447
A ROCK1 and ROCK2 inhibitor
-
GC12491
Narciclasine
A plant growth regulator with anticancer activity