Home >> Signaling Pathways >> TGF-β / Smad Signaling >> ROCK


ROCK (Rho-associated protein kinase) is a kinase belonging to the AGC family of serine-threonine kinases and takes part in regulating the shape and movement of cells by acting on the cytoskeleton.

  1. Cat.No. 产品名称 Information
  2. GC25482 GSK269962A HCl GSK269962A HCl (GSK269962B, GSK269962) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
  3. GC66338 ROCK1-IN-1 WAY-624704 is a novel Rho kinases (ROCK) inhibitor with an Ki of 17 nM.
  4. GC66050 Rho-Kinase-IN-2
  5. GC63716 Sovesudil hydrochloride
  6. GC63351 Sovesudil
  7. GC63333 Cotosudil
  8. GC63253 Verosudil
  9. GC49334 Chroman 1 (hydrochloride hydrate) A ROCK2 inhibitor
  10. GC50116 OXA 06 dihydrochloride Potent ROCK inhibitor
  11. GC50092 RKI 1447 dihydrochloride A ROCK1 and ROCK2 inhibitor
  12. GC50043 SR 3677 dihydrochloride A ROCK1 and ROCK2 inhibitor
  13. GC38898 CCG-222740 CCG-222740 is a Rho/MRTF pathway inhibitor. CCG-222740 decreases the activation of stellate cells in vitro and in vivo, by reducing the levels of alpha smooth muscle actin(α-SMA) expression.
  14. GC38791 GSK-25
  15. GC37947 Y-33075 An inhibitor of ROCK2
  16. GC37551 ROCK inhibitor-2
  17. GC37534 Ripasudil free base
  18. GC36208 H-1152 dihydrochloride H-1152 dihydrochloride (2HCl) is a membrane-permeable and selective inhibitor of Rho-associated protein kinase (ROCK). H-1152 inhibits ROCK2, PKA, PKC, PKG, AuroraA and CaMK2 with IC50 of 0.0120 μM, 3.03 μM, 5.68 μM, 0.360 μM, 0.745 μM and 0.180 μM, respectively.
  19. GC36207 H-1152 A ROCK inhibitor
  20. GC35442 Azaindole 1 A ROCK1 and ROCK2 inhibitor
  21. GC43286 CMPD101 A GRK2 and GRK3 inhibitor
  22. GC42747 Afuresertib (hydrochloride) A pan-Akt inhibitor
  23. GC41737 (S)-Glycyl-H-1152 (hydrochloride) A ROCK inhibitor
  24. GC34300 AR-13324 analog mesylate
  25. GC33901 Pentanoic acid Pentanoicacid是一种短链脂肪酸,是细菌代谢产物,与过敏性皮肤病有关系。Pentanoicacid能够激活ROCK信号通路。
  26. GC33310 Rho-Kinase-IN-1
  27. GC33120 ZINC00881524 A ROCK inhibitor
  28. GC32868 BDP5290

    BDP5290 is a potent inhibitor of ROCK and MRCK with IC50 values of 17nM, 230nM, 123nM and 100nM for MRCKβ, ROCK1, ROCK2, respectively .

  29. GC31952 ROCK-IN-1
  30. GC31883 ROCK2-IN-2
  31. GC19177 GSK180736A A ROCK1 and GRK2 inhibitor
  32. GC19034 AR-13324 mesylate AR-13324 是一种有效的 ROCK I 和 ROCK II 抑制剂,已被证明可在低浓度下诱导培养的人和猪 TM 细胞的形态学变化。
  33. GC10716 Netarsudil (AR-13324) ROCK抑制剂
  34. GC12402 LX7101 HCL A LIMK and ROCK inhibitor
  35. GC13759 SAR407899 A ROCK1 and ROCK2 inhibitor
  36. GC16289 SAR407899 hydrochloride A ROCK1 and ROCK2 inhibitor
  37. GC16475 Afuresertib A pan-Akt inhibitor
  38. GC12817 K–115 hydrochloride dihydrate K-115 hydrochloride dihydrate (K-115) 是 ROCK 的特异性抑制剂,对 ROCK2 和 ROCK1 的 IC50 分别为 19 和 51 nM。
  39. GC15170 SB 772077B dihydrochloride A ROCK1 and ROCK2 inhibitor
  40. GC17712 AT13148 A multi-AGC kinase inhibitor
  41. GC13869 Fasudil Fasudil (HA-1077; AT877) 是一种非特异性 RhoA/ROCK 抑制剂,对蛋白激酶也有抑制作用,对 ROCK1 的 Ki 为 0.33 μM,对 ROCK2 和 PKA 的 IC50 分别为 0.158 μM 和 4.58 μM、12.30 μM、1.650 μM ,PKC,PKG,分别。 Fasudil 也是一种有效的 Ca2+ 通道拮抗剂和血管扩张剂。
  42. GC17936 GSK269962A A ROCK1 and ROCK2 inhibitor
  43. GC10722 SR-3677 A ROCK1 and ROCK2 inhibitor
  44. GC15712 Y-27632 A ROCK inhibitor
  45. GC13423 Y-39983 dihydrochloride ROCK family inhibitor
  46. GC14289 Fasudil (HA-1077) HCl Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μ ;M, 1.650 μM 分别代表 ROCK2 和 PKA、PKC、PKG。 Fasudil (HA-1077) HCl 也是一种有效的 Ca2+ 通道拮抗剂和血管扩张剂。
  47. GC18119 GSK429286A A ROCK inhibitor
  48. GC11181 Thiazovivin A ROCK inhibitor
  49. GC12827 SLx-2119 A ROCK2 inhibitor
  50. GC15437 RKI-1447 A ROCK1 and ROCK2 inhibitor
  51. GC12491 Narciclasine A plant growth regulator with anticancer activity

Items 1 to 50 of 54 total

per page
  1. 1
  2. 2

Set Descending Direction