SMAD
SMAD are intracellular proteins that transduce extracellular signals from transforming growth factor beta ligands to the nucleus where they activate downstream gene transcription.
- Cat.No. 产品名称 Information
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GC44903
SMAD3 Inhibitor, SIS3
An inhibitor of TGF-β signaling
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GC41863
10,11-dehydro Curvularin
A natural mycotoxin
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GC34060
Disitertide (P144)
Disitertide (P144) (P144) 是一种肽类转化生长因子-β 1 (TGF-β1) 抑制剂,专门设计用于阻断与其受体的相互作用。 Disitertide (P144) (P144) 也是一种 PI3K 抑制剂和凋亡诱导剂。
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GC32914
EMT inhibitor-1
EMTinhibitor-1是Hippo,TGF-β和Wnt信号通路的抑制剂,并拥有抗肿瘤活性。
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GC32250
Chebulinic acid
An ellagitannin with diverse biological activities
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GC31950
Halofuginone hydrobromide (RU-19110 (hydrobromide))
Halofuginone (RU-19110) hydrobromid 是一种Ferifugine 衍生物,是一种竞争性脯氨酰-tRNA 合成酶抑制剂,Ki 为 18.3 nM。
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GC31650
Halofuginone (RU-19110)
Halofuginone (RU-19110) is the competitively inhibitor of prolyl-tRNA synthetase with Ki of 18.3 nM.It could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in mammal.
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GC19338
SRI-011381 hydrochloride
A TGF-β signaling activator
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GC17191
SIS3 HCl
SIS3HCl 是一种有效的选择性 Smad3 抑制剂,对 Smad3 磷酸化的 IC50 为 3 μM。
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GC15057
Kartogenin
A potent inducer of chondrocyte differentiation
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GC12790
Pirfenidone
A pyridone derivative with antifibrotic activity
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GC11604
LY364947
Inhibitor of TGF-β type-1 receptors
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GC17523
Hydrochlorothiazide
A thiazide diuretic
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GC16580
LDN-193189
An inhibitor of BMP receptors ALK1, ALK2, ALK3, and ALK6
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GC16793
RepSox
A selective inhibitor of ALK5
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GC14931
LDN193189 Hydrochloride
An inhibitor of BMP receptors ALK1, ALK2, ALK3, and ALK6
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GN10378
Oxymatrine
A natural antiviral and anti-fibrosis alkaloid
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GN10534
Asiaticoside
A saponin with significant wound healing activity