SMAD

SMAD are intracellular proteins that transduce extracellular signals from transforming growth factor beta ligands to the nucleus where they activate downstream gene transcription.

Products for SMAD

Cat.No. 产品名称 Information
GC44903 SMAD3 Inhibitor, SIS3 An inhibitor of TGF-β signaling
GC41863 10,11-dehydro Curvularin A natural mycotoxin
GC34060 Disitertide (P144) Disitertide (P144) (P144) 是一种肽类转化生长因子-β 1 (TGF-β1) 抑制剂，专门设计用于阻断与其受体的相互作用。 Disitertide (P144) (P144) 也是一种 PI3K 抑制剂和凋亡诱导剂。
GC32914 EMT inhibitor-1 EMTinhibitor-1是Hippo，TGF-β和Wnt信号通路的抑制剂，并拥有抗肿瘤活性。
GC32250 Chebulinic acid An ellagitannin with diverse biological activities
GC31950 Halofuginone hydrobromide (RU-19110 (hydrobromide)) Halofuginone (RU-19110) hydrobromid 是一种Ferifugine 衍生物，是一种竞争性脯氨酰-tRNA 合成酶抑制剂，Ki 为 18.3 nM。
GC31650 Halofuginone (RU-19110) Halofuginone (RU-19110) is the competitively inhibitor of prolyl-tRNA synthetase with Ki of 18.3 nM.It could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in mammal.
GC19338 SRI-011381 hydrochloride A TGF-β signaling activator
GC17191 SIS3 HCl
SIS3HCl 是一种有效的选择性 Smad3 抑制剂，对 Smad3 磷酸化的 IC50 为 3 μM。
GC15057 Kartogenin A potent inducer of chondrocyte differentiation
GC12790 Pirfenidone A pyridone derivative with antifibrotic activity
GC11604 LY364947 Inhibitor of TGF-β type-1 receptors
GC17523 Hydrochlorothiazide A thiazide diuretic
GC16580 LDN-193189
An inhibitor of BMP receptors ALK1, ALK2, ALK3, and ALK6
GC16793 RepSox A selective inhibitor of ALK5
GC14931 LDN193189 Hydrochloride An inhibitor of BMP receptors ALK1, ALK2, ALK3, and ALK6
GN10378 Oxymatrine A natural antiviral and anti-fibrosis alkaloid
GN10534 Asiaticoside A saponin with significant wound healing activity