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Home >> Signaling Pathways >> Obesity, Appetite Control & Diabetes

Obesity, Appetite Control & Diabetes(肥胖，食欲控制 & 糖尿病)

Obesity, Appetite Control & Diabetes

Satiety, appetite, and craving are CNS drives, whereas metabolism and energy utilization are peripheral endocrine actions.
Stephen M. Stahl, M.D., Ph.D. read more

Products for  Obesity, Appetite Control & Diabetes

  1. Cat.No. 产品名称 Information
  2. GC43779 Glycolithocholic Acid (sodium salt) Glycolithocholic acid is a glycine conjugate of lithocholic acid, a bile acid.
  3. GC43778 Glycolithocholic Acid Glycolithocholic acid 是一种内源性代谢物，是一种与甘氨酸结合的次级胆汁酸。
  4. GC43773 Glyburide (potassium salt) Glyburide is a sulfonylurea and an inhibitor of sulfonylurea receptor 1 (SUR1) linked to ATP-sensitive potassium channel Kir6.2 (IC50 = 4.3 nM).
  5. GC43768 Glucocerebrosides (Gaucher's spleen) Glucocerebrosides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase.
  6. GC43766 Glucagon Receptor Antagonist Inactive Control An inactive control for glucagon receptor antagonist I
  7. GC43764 GLP-2 (human) (trifluoroacetate salt) Glucagon-like peptide-2 (GLP-2) is an endogenous peptide hormone formed in L cells of the small and large intestine by cleavage of proglucagon in response to nutrient ingestion.
  8. GC43754 Ghrelin (rat) (trifluoroacetate salt) Ghrelin is an endogenous gastrointestinal hormone and neuropeptide that binds to the growth hormone (GH) secretagogue receptor (GHS-R).
  9. GC43732 Ganglioside GM3 Mixture (sodium salt) Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation.
  10. GC43671 FKGK 18 FKGK 18 是一种选择性 VIA 组非钙依赖性磷脂酶 A2 (GVIA iPLA2) 抑制剂。
  11. GC43408 Deoxycholic Acid (sodium salt hydrate) 脱氧胆酸（胆酸）钠水合物是一种胆汁酸，是肠道代谢的副产物，可激活 G 蛋白偶联胆汁酸受体 TGR5。
  12. GC43376 Dapagliflozin-3-O-β-D-Glucuronide

    Dapagliflozin-3-O-β-D-glucuronide is a metabolite of dapagliflozin.
  13. GC43215 CCK Octapeptide (non-sulfated), (trifluoroacetate salt) Cholecystokinin (CCK) octapeptide is a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety.
  14. GC43180 CAY10592 Peroxisome proliferator-activated receptors (PPARs) α, δ, γ are ligand-activated nuclear transcription factors involved in the regulation of energy homeostasis as well as insulin sensitivity and glucose metabolism.
  15. GC43140 Captopril Disulfide 卡托普利二硫化物是卡托普利的代谢物，具有抗高血压活性。
  16. GC43113 Caerulein (acetate) Caerulein is an oligopeptide originally isolated from skin extracts of H.
  17. GC43075 C24 dihydro Ceramide (d18:0/24:0)

    C24 dihydro Ceramide is a sphingolipid that has been found in the stratum corneum of human skin.
  18. GC43068 C20 Sphingomyelin (d18:1/20:0) C20 Sphingomyelin is a naturally occurring sphingolipid.
  19. GC43055 C18:1 Ceramide (d18:1/18:1(9Z))

    C18:1 Ceramide is a naturally occurring ceramide.
  20. GC43048 C18 dihydro Ceramide (d18:0/18:0)

    A bioactive sphingolipid
  21. GC43047 C18 Ceramide (d18:1/18:0)

    C18 Ceramide is an endogenous bioactive sphingolipid.
  22. GC43035 C16 Sphingomyelin (d18:1/16:0) Sphingomyelins are complex membrane lipids composed of phosphorylcholine, sphingosine, and an acylated group, such as a fatty acid.
  23. GC43033 C16 Lactosylceramide (d18:1/16:0) C16 Lactosylceramide is an endogenous bioactive sphingolipid.
  24. GC43022 C14 Ceramide (d18:1/14:0)

    C14 Ceramide is an endogenous ceramide generated by ceramide synthase 6.
  25. GC42805 AN-7 α-Lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form.
  26. GC42796 Amylin (human) (trifluoroacetate salt) Amylin is a 37-residue peptide hormone secreted from pancreatic β-cells that reduces food intake, decreases glucagon secretion, slows gastric emptying, and increases satiety.
  27. GC42791 Amorfrutin B Amorfrutin B is a partial agonist of the peroxisome proliferator-activated receptor γ (PPARγ; Ki = 19 nM and EC50 = 73 nM) that was first isolated from A.
  28. GC42786 Aminoacetone (hydrochloride) Aminoacetone is a threonine and glycine catabolite that can be converted to methylglyoxal by amine oxidases.
  29. GC42674 ABD459 ABD459 is a neutral antagonist of the central cannabinoid 1 (CB1) receptor (Ki = 8.6 nM).
  30. GC42620 8-Aminopyrene-1,3,6-trisulfonic Acid (sodium salt) 8-Aminopyrene-1,3,6-trisulfonic Acid（钠盐）是一种水溶性阴离子荧光染料。
  31. GC42434 4-methyl-2-Oxovalerate (sodium salt) 4-methyl-2-Oxovalerate is an immediate precursor and metabolite of L-leucine.
  32. GC42411 4-hydroxy Nonenal Alkyne 4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid.
  33. GC42291 3-Hydroxyisobutyrate (sodium salt)

    3-Hydroxyisobutyrate (3-HIB) is an intermediate in the metabolism of the branched-chain amino acid valine that is secreted by skeletal muscle.
  34. GC42035 1-Palmitoyl-2-Stearoyl-3-Oleoyl-rac-glycerol 1-Palmitoyl-2-stearoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains palmitic, stearic, and oleic acid at the sn-1, sn-2, and sn-3 positions, respectively.
  35. GC41907 13C C16 Sphingomyelin (d18:1/16:0) 13C C16 Sphingomyelin is an isotopically enriched form of C16 sphingomyelin with carbon-13 occurring on the fatty acid portion.
  36. GC41873 10-Thiastearic Acid Heteroatom-substituted fatty acids have been observed to modulate the extension and desaturating of fatty acids, and to influence their distribution within phospholipids pools.
  37. GC41794 1,2-Diheptanoyl-sn-glycero-3-PC 1,2-Diheptanoyl-sn-glycero-3-PC (DHPC-C7) is a synthetic phosphatidylcholine containing the short-chain (7:0) heptanoic acid at the sn-1 and sn-2 positions.
  38. GC41777 1,2,3-Tripalmitoleoyl-rac-glycerol 1,2,3-Tripalmitoleoyl-rac-glycerol is a triacylglycerol that contains palmitoleic acid at the sn-1, sn-2, and sn-3 positions.
  39. GC41647 Pinolenic Acid

    Pinolenic acid is a polyunsaturated fatty acid found in Korean pine (Pinus orientalis) and maritime pine (Pinus pinaster) seed oils.
  40. GC41601 CAY10591 CAY10591 是一种有效的 Sirt1 激活剂，可抑制 TNF-α；以剂量依赖的方式。
  41. GC41406 AMP-Deoxynojirimycin The lipid messenger ceramide is converted to glucosylceramide by glucosylceramide synthase (GCS).
  42. GC41339 Pioglitazone Ketone Pioglitazone ketone is an active metabolite of the PPARγ agonist pioglitazone.
  43. GC40912 Glycohyocholic Acid 糖球胆酸 (GHCA) 是初级胆汁酸球胆酸的甘氨酸共轭形式。
  44. GC40889 Benzomalvin A Benzomalvin A 是一种从青霉分离的神经激肽受体的强效拮抗剂。
  45. GC40812 all-cis-4,7,10,13,16-Docosapentaenoic Acid Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oils.
  46. GC40788 Pinolenic Acid ethyl ester Pinolenic acid is a polyunsaturated fatty acid found in Korean pine (Pinus orientalis) and maritime pine (Pinus pinaster) seed oils.
  47. GC40713 Pinolenic Acid methyl ester Pinolenic acid is a polyunsaturated fatty acid found in Korean pine (Pinus orientalis) and maritime pine (Pinus pinaster) seed oils.
  48. GC40666 Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate (DDC) inhibits heme production by inhibiting ferrochelatase, the enzyme that catalyzes the addition of Fe2+ to protoporphyrin IX to create heme B.
  49. GC40636 Amorfrutin A Amorfrutin A is an isoprenoid-substituted benzoic acid natural product found in the fruit of A.
  50. GC40384 CAY10410 CAY10410 is an analog of prostaglandin D2/prostaglandin J2 (PGD2/PGJ2) with structural modifications intended to give it PPARγ ligand activity and resistance to metabolism.
  51. GC40325 9-PAHSA Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity.

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