P450
Cytochrome P450 are a family of heme-containing monoxygenases catalyzing the metabolism of xenobiotics in the body where P450 enzymes use O2 and two electrons provided by NAD(P)H with the help of redox partner flavoproteins and iron-sulfur proteins to catalyze the monooxygenation of a variety of substrates. Based on how electrons from NAD(P)H are delivered to the catalytic site, P450 enzymes are divided into four classes, including Class I requiring both an FAD-containing reductase and an iron sulfur redoxin, Class II requiring only an FAD/FMN-containg P450 reductase, Class III requiring no electron donor and Class IV requiring electrons directly from NAD(P)H.
Products for P450
- Cat.No. 产品名称 Information
- GN10425 Schisandrin A A lignan with diverse biological activities
- GN10150 Apigenin 芹菜素(Apigenin,API)是一种竞争性 CYP2C9 抑制剂,Ki 为2 µM。.
- GN10549 Ginsenoside Rd A natural steroid glycoside with diverse effects
- GN10032 Ginsenoside F1 A ginsenoside with diverse biological activities
- GN10330 8-Methoxypsoralen 8-Methoxypsoralen (8-Methoxypsoralen) 是一种有效的 CYP(细胞色素 P-450)三环呋喃香豆素自杀抑制剂,是一种用于治疗银屑病、湿疹、白癜风和一些皮肤淋巴瘤以及将皮肤暴露在阳光下的药物。
- GN10241 5-Methoxypsoralen A furanocoumarin derivative with diverse biological activities