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P450

Cytochrome P450 are a family of heme-containing monoxygenases catalyzing the metabolism of xenobiotics in the body where P450 enzymes use O2 and two electrons provided by NAD(P)H with the help of redox partner flavoproteins and iron-sulfur proteins to catalyze the monooxygenation of a variety of substrates. Based on how electrons from NAD(P)H are delivered to the catalytic site, P450 enzymes are divided into four classes, including Class I requiring both an FAD-containing reductase and an iron sulfur redoxin, Class II requiring only an FAD/FMN-containg P450 reductase, Class III requiring no electron donor and Class IV requiring electrons directly from NAD(P)H.

Products for  P450

  1. Cat.No. 产品名称 Information
  2. GC41319 (±)5(6)-EpETE methyl ester A stable derivative of 5(6)-EpETE
  3. GC41312 5-hydroxy Omeprazole A major metabolite of omeprazole
  4. GC41302 6',7'-Epoxybergamottin A potent CYP3A4 inhibitor from grapefruit
  5. GC41300 17β-hydroxy Exemestane An active metabolite of exemestane
  6. GC41288 (±)17(18)-EpETE-Ethanolamide An ω-3 endocannabinoid epoxide
  7. GC41264 CAY10434 A potent, selective 20-HETE synthase inhibitor
  8. GC41212 (±)10(11)-EpDPA A DHA epoxygenase metabolite
  9. GC41203 (±)7(8)-EpDPA A DHA epoxygenase metabolite
  10. GC41201 (±)4(5)-DiHDPA lactone A lactone derived from DHA
  11. GC41199 (±)19(20)-EpDPA A DHA epoxygenase metabolite
  12. GC41194 (±)16(17)-EpDPA A DHA congener of (±)14(15)-EpETrE
  13. GC41191 (±)13(14)-EpDPA A DHA epoxygenase metabolite
  14. GC41143 (±)11,12-DiHETE An EPA metabolite
  15. GC41128 5(S),6(R)-11-trans DiHETE A metabolite of LTA4
  16. GC41120 (±)8,9-DiHETE A major metabolite of EPA
  17. GC41119 (±)5(6)-DiHETE Possible metabolite of EPA
  18. GC41117 (±)17(18)-DiHETE An epoxygenase metabolite of EPA
  19. GC41104 20-carboxy Arachidonic Acid A metabolite of 20-HETE
  20. GC40968 21-hydroxy Eplerenone A major metabolite of eplerenone
  21. GC40954 (±)-N-3-Benzylnirvanol A racemic mixture of (+)-N-3-benzylnirvanol and (–)-N-3-benzylnirvanol
  22. GC40906 (±)7(8)-EpDTE An oxylipin
  23. GC40905 (±)19(20)-EpDTE An oxylipin
  24. GC40802 (±)12(13)-DiHOME A diol form of (±)12,13-EpOME
  25. GC40801 (±)9(10)-DiHOME A diol form of (±)9(10)-EpOME
  26. GC40638 Alclometasone Dipropionate A corticosteroid
  27. GC40572 7-keto Cholesterol A bioactive oxysterol
  28. GC40534 20-hydroxy Prostaglandin F2α A CYP450 ω-oxidation metabolite of PGF
  29. GC40466 (±)11(12)-EET A racemic version of a CYP450 metabolite of arachidonic acid
  30. GC40465 9(S)-HETE A monohydroxy fatty acid and RXRγ agonist
  31. GC40464 9(R)-HETE Enantiomer of (±)9-HETE; RXRγ activator
  32. GC40458 19(S)-HETE Potent vasodilator of renal preglomerular vessels
  33. GC40457 19(R)-HETE A potent vasodilator of renal arterioles
  34. GC40456 17(S)-HETE A potent inhibitor of proximal tubule ATPase activity
  35. GC40455 17(R)-HETE An inactive isomer of 17-HETE
  36. GC40454 16(S)-HETE A potent inhibitor of proximal tubule ATPase activity
  37. GC40447 12(R)-HETE An active metabolite of arachidonic acid
  38. GC40443 (±)9-HETE A monohydroxy fatty acid
  39. GC40438 (±)5(6)-EET A racemic version of a CYP450 metabolite of arachidonic acid
  40. GC40437 (±)5(6)-DiHET lactone A lactone form of (±)5(6)-DiHET
  41. GC40436 (±)18-HETE A vasodilator of renal arterioles
  42. GC40435 (±)17-HETE A potent inhibitor of proximal tubule ATPase activity
  43. GC40434 (±)16-HETE A potent inhibitor of proximal tubule ATPase activity
  44. GC40430 (±)14(15)-EET An arachidonic acid metabolite
  45. GC40425 14,15-EE-8(Z)-E A potent vasodilator
  46. GC40424 14,15-EE-5(Z)-E An antagonist of EDHF-mediated vasodilation
  47. GC40388 (±)19(20)-DiHDTE An oxylipin
  48. GC40386 (±)11(12)-EpETE Epoxygenase metabolite of EPA
  49. GC40377 20-HEPE An EPA metabolite
  50. GC40365 (±)8(9)-EpETE Epoxygenase metabolite of EPA
  51. GC40363 (±)5(6)-DiHETE lactone A lactone form of (±)5(6)-DiHETE

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