Sirtuin(Sirtuin蛋白)
Silent information regulator 2 (Sir2) proteins, also known as sirtuins, are a family of nicotine adenine dinucleotide (NAD) dependent protein deacetylases in organisms ranging from bacteria to humans that are characterized by the presence of a unique and highly conserved catalytic domain of approximately 260 amino acids. Sirtuins are divided into 5 classes, including Class I (subclasses Ia, Ib and Ic), Class II, Class III, Class IV (subclasses IVa and IVb) and Class U (Gram-positive bacteria specific). The catalytic domain of sirtuins is comprised of two bilobed globular domains, the large domain containing the NAD-binding pocket and the small domain binding the acetyl-lysine substrate.
Products for Sirtuin
- Cat.No. 产品名称 Information
- GC14755 Inauhzin A selective SIRT1 inhibitor
- GC12337 Tenovin-3 A small molecule activator of p53
- GC16436 Tenovin-6 A small molecule activator of p53
- GC10555 Splitomicin Inhibitor of yeast Sir2p
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GC15109
SRT2104 (GSK2245840)
SRT2104 (GSK2245840) is a highly selective small-molecule activator of Sirtuin 1 (SIRT1).
- GC14165 Tenovin-1 A small molecule activator of p53
- GC14945 Sirtinol Inhibitor of sirtuin deacetylases
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GC14553
Resveratrol
白藜芦醇(转-白藜芦醇;SRT501)是一种植物抗菌素,具有强大的还原剂作用
- GC10635 EX 527 (SEN0014196) A SIRT1 inhibitor
- GC17101 SRT1720 HCl SRT1720 HCl is an activator of SIRT1 (EC1.
- GN10030 Fisetin A flavonoid with diverse biological activities
- GN10413 Agrimol B A polyphenol with adipogenesis inhibitory and anticancer activities
- GN10420 Ophiopogonin D' A steroid glycoside with diverse biological activities
- GN10473 Ginkgolide C A PAF receptor antagonist
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GN10347
Nicotinamide (Vitamin B3)
An amide form of niacin