QTRTD1 Human
目录号 : GP22215Queuine TRNA-Ribosyltransferase Domain Containing 1 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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QTRTD1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 438 amino acids (1-415 a.a) and having a molecular mass of 49.1kDa.QTRTD1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| Purity | Greater than 95.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Queuine TRNA-Ribosyltransferase Domain Containing 1; EC 2.4.2.29; Queuine TRNA-Ribosyltransferase Domain-Containing Protein 1; QTRTD1. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMKLSLTK VVNGCRLGKI KNLGKTGDHT MDIPGCLLYT KTGSAPHLTH HTLHNIHGVP AMAQLTLSSL AEHHEVLTEY KEGVGKFIGM PESLLYCSLH DPVSPCPAGY VTNKSVSVWS VAGRVEMTVS KFMAIQKALQ PDWFQCLSDG EVSCKEATSI KRVRKSVDRS LLFLDNCLRL QEESEVLQKS VIIGVIEGGD VMEERLRSAR ETAKRPVGGF LLDGFQGNPT TLEARLRLLS SVTAELPEDK PRLISGVSRP DEVLECIERG VDLFESFFPY QVTERGCALT FSFDYQPNPE ETLLQQNGTQ EEIKCMDQIK KIETTGCNQE ITSFEINLKE KKYQEDFNPL VRGCSCYCCK NHTRAYIHHL LVTNELLAGV LLMMHNFEHY FGFFHYIREA LKSDKLAQLK ELIHRQAS. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | QTRTD1 protein solution (0.25mg/ml) containing Phosphatebuffered saline (pH7.4) 30% glycerol, 2mM DTT, 1mM EDTA and 0.1mM PMSF. | ||
Queuine TRNA-Ribosyltransferase Domain Containing 1, also known asQTRTD1 act together with QTRT1 to form an active queuinetRNA-ribosyltransferase. QTRTD1 exchanges queuine for the guanine at the wobbleposition of tRNAs along with GUN anticodons (tRNA-Asp,-Asn,-His and -Tyr), inthat way forming the hypermodified nucleoside queuosine.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.