PON1 Human
目录号 : GP22121Paraoxonase-1 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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Paraoxonase-1 Isoform Human Recombinant is expressed in E. coli, fused to a 4.5kDa amino terminal hexahistidine tag, having a total molecular weight of 42.9kDa.The PON1 purified by proprietary chromatographic techniques.
| Purity | Greater than 95% as determined by SDS-PAGE. Single band on Western Blot. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Serum paraoxonase; arylesterase 1; EC 3.1.1.2; EC 3.1.8.1; PON 1; Serum aryldialkylphosphatase 1; A-esterase 1; Aromatic esterase 1; K-45; ESA; PON. | ||
| Amino Acid Sequence | MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPNGLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTFTDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYGTNDHYFLDPYLRSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAELLAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPPASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCELZ. | ||
| Stability | Store at 4°C if entire vial will be used within 1-2 weeks.Store, frozen at -20°C for longer periods of time.Avoid multiple freeze-thaw cycles. | ||
| Formulation | PON1 is supplied in 20mM Tris-HCl pH 8.0 and 50% glycerol. | ||
Paraoxonase 1 also called Esterase-A is involved in the detoxification of organophosphate insecticides such as parathion. Paraoxonase 1 may also confer protection against coronary artery disease by destroying proinflammatory oxidized lipids present in oxidized low-density lipoproteins (LDLs).
Store at 4°C if entire vial will be used within 1-2 weeks.Store, frozen at -20°C for longer periods of time.Avoid multiple freeze-thaw cycles.