POLR2D Human
目录号 : GP22113Polymerase II Polypeptide D Human Recombinant
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 90% as determined by SDS-PAGE. | Source | E.coli. |
Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | HSRBP4; HSRPB4; RBP4; RPB16; DNA-directed RNA polymerase II subunit RPB4; RNA polymerase II subunit B4; DNA-directed RNA polymerase II subunit D; RNA polymerase II 16 kDa subunit; POLR2D. | ||
Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMAAGGSD PRAGDVEEDA SQLIFPKEFE TAETLLNSEV HMLLEHRKQQ NESAEDEQEL SEVFMKTLNY TARFSRFKNR ETIASVRSLL LQKKLHKFEL ACLANLCPET AEESKALIPS LEGRFEDEEL QQILDDIQTK RSFQY. | ||
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
Formulation | The POLR2D solution (1mg/ml) contains 20mM Tris-HClbuffer (pH 8.0), 0.4M Urea and 10% glycerol. |
Polymerase II Polypeptide D (POLR2D) is a member of the eukaryotic RPB4RNA polymerase subunit family. POLR2D is the fourth largest subunit of RNApolymerase II. Pol II is the main element of the basal RNA polymerase IItranscription machinery. polymerase is responsible forsynthesizing messenger RNA in eukaryotes. In yeast, POLR2D subunit is connectedwith the polymerase under suboptimalgrowth conditions and might have a stress protective role. POLR2D catalyzes thetranscription of DNA into RNA by the 4 ribonucleoside triphosphates assubstrates.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.