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POLR2D Human

目录号 : GP22113

Polymerase II Polypeptide D Human Recombinant

POLR2D Human Chemical Structure

规格 价格 库存 购买数量
5μg
¥840.00
5-10工作日
20μg
¥2,030.00
5-10工作日
1mg
¥37,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

POLR2D Human Recombinant produced in E.coli is a single,non-glycosylated polypeptide chain containing 165 amino acids (1-142) andhaving a molecular mass of 18.7kDa.POLR2D is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 90% as determined by SDS-PAGE. Source E.coli.
Phycical Appearance Sterile Filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms HSRBP4; HSRPB4; RBP4; RPB16; DNA-directed RNA polymerase II subunit RPB4; RNA polymerase II subunit B4; DNA-directed RNA polymerase II subunit D; RNA polymerase II 16 kDa subunit; POLR2D.
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMAAGGSD PRAGDVEEDA SQLIFPKEFE TAETLLNSEV HMLLEHRKQQ NESAEDEQEL SEVFMKTLNY TARFSRFKNR ETIASVRSLL LQKKLHKFEL ACLANLCPET AEESKALIPS LEGRFEDEEL QQILDDIQTK RSFQY.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation The POLR2D solution (1mg/ml) contains 20mM Tris-HClbuffer (pH 8.0), 0.4M Urea and 10% glycerol.

Introduction

Polymerase II Polypeptide D (POLR2D) is a member of the eukaryotic RPB4RNA polymerase subunit family. POLR2D is the fourth largest subunit of RNApolymerase II. Pol II is the main element of the basal RNA polymerase IItranscription machinery. polymerase is responsible forsynthesizing messenger RNA in eukaryotes. In yeast, POLR2D subunit is connectedwith the polymerase under suboptimalgrowth conditions and might have a stress protective role. POLR2D catalyzes thetranscription of DNA into RNA by the 4 ribonucleoside triphosphates assubstrates.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.