POGLUT1 Human
目录号 : GP22110Protein O-Glucosyltransferase 1 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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POGLUT1 Human Recombinant produced in in Sf9 Baculoviruscells is a single, non-glycosylated polypeptide chain containing 377 aminoacids (24-392a.a) and having a molecular mass of 44.5kDa (Migrates at 40-57kDaon SDS-PAGE under reducing conditions).POGLUT1 is fused to a 8 amino acid His-tag at C-Terminusand purified by proprietary chromatographic techniques.
| Purity | Greater than 90% as determined by SDS-PAGE. | Source | Sf9,Baculovirus cells. |
| Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | POGLUT1; C3orf9; CLP46; hCLP46; KDELCL1; KTELC1; ProteinO-glucosyltransferase 1; CAP10-like 46 kDa protein; KTEL motif-containingprotein 1; Myelodysplastic syndromes relative protein; O-glucosyltransferaseRumi homolog; hRumi; Protein O-xylosyltransferase; MDSRP. | ||
| Amino Acid Sequence | RQKESGSKWKVFIDQINRSL ENYEPCSSQN CSCYHGVIEE DLTPFRGGIS RKMMAEVVRR KLGTHYQITK NRLYRENDCMFPSRCSGVEH FILEVIGRLP DMEMVINVRD YPQVPKWMEP AIPVFSFSKT SEYHDIMYPA WTFWEGGPAVWPIYPTGLGR WDLFREDLVR SAAQWPWKKK NSTAYFRGSR TSPERDPLIL LSRKNPKLVD AEYTKNQAWKSMKDTLGKPA AKDVHLVDHC KYKYLFNFRG VAASFRFKHL FLCGSLVFHV GDEWLEFFYP QLKPWVHYIPVKTDLSNVQE LLQFVKANDD VAQEIAERGS QFIRNHLQMD DITCYWENLL SEYSKFLSYN VTRRKGYDQIIPKMLKTELL EHHHHHH. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | ||
| Formulation | The POGLUT1 solution (0.25mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 10% glycerol. | ||
POGLUT1 is a homologue of Rumi fromDrosophila, an endoplasmic reticulum (ER)-retaining glucosyltransferase which catalyzesthe transfer of glucose and xylose from UDP-glucose and UDP-xylose,respectively, to EGF repeats on the consensus sequence C-X-S-X-P-C. POGLUT1 positivelyregulates Notch signaling without affecting Notch ligand binding.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.