PDHX Human
目录号 : GP22057Pyruvate Dehydrogenase Complex, Component X Human Recombinant
Sample solution is provided at 25 µL, 10mM.
PDHX Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 471 amino acids (54-501 a.a) and having a molecular mass of 50.4kDa. PDHX is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Purity | Greater than 85.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | DLDBP; E3BP; OPDX; PDX1; proX; Pyruvate Dehydrogenase Complex; Component X; Dihydrolipoamide Dehydrogenase-Binding Protein Of Pyruvate Dehydrogenase Complex; Lipoyl-Containing Pyruvate Dehydrogenase Complex Component X; Pyruvate Dehydrogenase Complex; Lipoyl-Containing Component X; Pyruvate Dehydrogenase Complex; E3-Binding Protein Subunit; Pyruvate Dehydrogenase Protein X Component; Mitochondrial; E3-Binding Protein. | ||
Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSGDPIKIL MPSLSPTMEE GNIVKWLKKE GEAVSAGDAL CEIETDKAVV TLDASDDGIL AKIVVEEGSK NIRLGSLIGL IVEEGEDWKH VEIPKDVGPP PPVSKPSEPR PSPEPQISIP VKKEHIPGTL RFRLSPAARN ILEKHSLDAS QGTATGPRGI FTKEDALKLV QLKQTGKITE SRPTPAPTAT PTAPSPLQAT AGPSYPRPVI PPVSTPGQPN AVGTFTEIPA SNIRRVIAKR LTESKSTVPH AYATADCDLG AVLKVRQDLV KDDIKVSVND FIIKAAAVTL KQMPDVNVSW DGEGPKQLPF IDISVAVATD KGLLTPIIKD AAAKGIQEIA DSVKALSKKA RDGKLLPEEY QGGSFSISNL GMFGIDEFTA VINPPQACIL AVGRFRPVLK LTEDEEGNAK LQQRQLITVT MSSDSRVVDD ELATRFLKSF KANLENPIRL A. | ||
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
Formulation | PDHX protein solution (0.25mg/ml) containing Phosphate buffer saline (pH 7.4) and 20% glycerol, 1mM DTT. |
Pyruvate Dehydrogenase Complex, Component X, also known as PDHX, encodesthe E3 binding protein subunit of the PDH complex which contains 3 catalyticsubunits. PDHX tethers E3 dimers to the E2 core of the pyruvate dehydrogenasecomplexes of eukaryotes. This specific binding is critical for a functional PDHcomplex.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.