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PCOLCE Human

目录号 : GP22052

Procollagen C-Endopeptidase Enhancer Human Recombinant

PCOLCE Human Chemical Structure

规格 价格 库存 购买数量
5μg
¥840.00
5-10工作日
25μg
¥2,030.00
5-10工作日
1mg
¥37,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

PCOLCE Human Recombinant produced in E.Coli is a single, non-glycosylatedpolypeptide chain containing 447 amino acids (26-449 a.a) and having amolecular mass of 47.9kDa.PCOLCE is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 85.0% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms ProcollagenC-Endopeptidase Enhancer; Procollagen C-Proteinase Enhancer 1; Type IProcollagen COOH-Terminal Proteinase Enhancer; Type 1 Procollagen C-ProteinaseEnhancer Protein; Procollagen COOH-Terminal Proteinase Enhancer 1; PCPE-1; PCPE1;Procollagen; Type 1; COOH-Terminal Proteinase Enhancer; ProcollagenC-Endopeptidase Enhancer 1; COOH-Terminal Proteinase Enhancer; Procollagen;Type 1; PCPE; Procollagen C-endopeptidase enhancer 1.
Amino Acid Sequence MGSSHHHHHHSSGLVPRGSH MGSQTPNYTRPVFLCGGDVK GESGYVASEG FPNLYPPNKE CIWTITVPEG QTVSLSFRVF DLELHPACRY DALEVFAGSGTSGQRLGRFC GTFRPAPLVA PGNQVTLRMT TDEGTGGRGF LLWYSGRATS GTEHQFCGGR LEKAQGTLTTPNWPESDYPP GISCSWHIIA PPDQVIALTF EKFDLEPDTY CRYDSVSVFN GAVSDDSRRL GKFCGDAVPGSISSEGNELL VQFVSDLSVT ADGFSASYKT LPRGTAKEGQ GPGPKRGTEP KVKLPPKSQP PEKTEESPSAPDAPTCPKQC RRTGTLQSNF CASSLVVTAT VKSMVREPGE GLAVTVSLIG AYKTGGLDLP SPPTGASLKFYVPCKQCPPM KKGVSYLLMG QVEENRGPVL PPESFVVLHR PNQDQILTNL SKRKCPSQPV RAAASQD.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation PCOLCE protein solution (1mg/ml) containing 20mM Tris-HClbuffer (pH 8.0) and 10% glycerol.

Introduction

Procollagen C-endopeptidase enhancer 1, also known as PCOLCE binds tothe C-terminal propeptide of type I procollagen and enhances procollagenC-proteinase activity. In addition, C-terminal processed part of PCPE (CT-PCPE)has a metalloproteinase inhibitory activity. Among the diseases which are associatedwith PCOLCE: bone fracture & oculopharyngeal muscular dystrophy.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.