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NT5C3B Human

目录号 : GP22014

5'-Nucleotidase, Cytosolic IIIB Human Recombinant

NT5C3B Human Chemical Structure

规格 价格 库存 购买数量
5μg
¥840.00
5-10工作日
20μg
¥2,030.00
5-10工作日
1mg
¥37,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

NT5C3B Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 323 amino acids (1-300 a.a) and havinga molecular mass of 36.8kDa.NT5C3B is fusedto a 23 amino acid His-tag at N-terminus & purified by proprietarychromatographic techniques.

Product Data

Purity Greater than 85.0% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile Filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms NT5C3L; 7-methylguanosine phosphate-specific5'-nucleotidase; Cytosolic 5'-nucleotidase 3B; Cytosolic 5'-nucleotidaseIII-like protein; cN-III-like protein; N(7)-methylguanylate 5'-phosphatase.
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMAEEVST LMKATVLMRQ PGRVQEIVGA LRKGGGDRLQ VISDFDMTLSRFAYNGKRCP SSYNILDNSK IISEECRKEL TALLHHYYPI EIDPHRTVKE KLPHMVEWWT KAHNLLCQQKIQKFQIAQVV RESNAMLREG YKTFFNTLYH NNIPLFIFSA GIGDILEEII RQMKVFHPNI HIVSNYMDFNEDGFLQGFKG QLIHTYNKNS SACENSGYFQ QLEGKTNVIL LGDSIGDLTM ADGVPGVQNI LKIGFLNDKVEERRERYMDS YDIVLEKDET LDVVNGLLQH ILCQGVQLEM QGP.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation NT5C3B protein solution (1mg/ml) containing PhosphateBuffered Saline (pH7.4), 20% glycerol and1mM DTT.

Introduction

7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) includes transferase activity and nucleotide binding. Among NT5C3Bбпs related super-pathways are adenosine nucleotides degradation II and Pyrimidine metabolism. NT5C3B hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate. The specific activity for m(7)GMP guards cells against undesired retrieval of m(7)GMP and its incorporation into nucleic acids. In addition, NT5C3B has weak activity for CMP.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.