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NMT1 Human

目录号 : GP22005

N-Myristoyltransferase 1 Human Recombinant

NMT1 Human Chemical Structure

规格 价格 库存 购买数量
5μg
¥840.00
5-10工作日
20μg
¥2,030.00
5-10工作日
1mg
¥37,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

NMT1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 519 amino acids (1-496 a.a) and having a molecular mass of 59.2kDa.NMT1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 95.0% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile Filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms N-Myristoyltransferase 1; NMT; Myristoyl-CoA:Protein N-Myristoyltransferase 1; Type I N-Myristoyltransferase; EC 2.3.1.97; Myristoyl-CoA:Protein;N- Myristoyltransferase; Glycylpeptide N-Tetradecanoyltransferase 1;Peptide N-Myristoyltransferase 1;Alternative; Short Form NMT-S; Short Form NMT-S;Long Form; NMT-L; Alternative; Long Form; NMT-L; NMT 1.
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMADESET AVKPPAPPLP QMMEGNGNGH EHCSDCENEE DNSYNRGGLS PANDTGAKKK KKKQKKKKEK GSETDSAQDQ PVKMNSLPAE RIQEIQKAIE LFSVGQGPAK TMEEASKRSY QFWDTQPVPK LGEVVNTHGP VEPDKDNIRQ EPYTLPQGFT WDALDLGDRG VLKELYTLLN ENYVEDDDNM FRFDYSPEFL LWALRPPGWL PQWHCGVRVV SSRKLVGFIS AIPANIHIYD TEKKMVEINF LCVHKKLRSK RVAPVLIREI TRRVHLEGIF QAVYTAGVVL PKPVGTCRYW HRSLNPRKLI EVKFSHLSRN MTMQRTMKLY RLPETPKTAG LRPMETKDIP VVHQLLTRYL KQFHLTPVMS QEEVEHWFYP QENIIDTFVV ENANGEVTDF LSFYTLPSTI MNHPTHKSLK AAYSFYNVHT QTPLLDLMSD ALVLAKMKGF DVFNALDLME NKTFLEKLKF GIGDGNLQYY LYNWKCPSMG AEKVGLVLQ.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation NMT1 protein solution (1mg/ml) containing Phosphate buffered saline (pH7.4).

Introduction

Myristate, a rare 14-carbon saturated fatty acid, is co-translationallyattached by an amide linkage to the N-terminal glycine residue of cellular& viral proteins with various functions. N-Myristoyltransferase 1, alsoknown as NMT1 catalyzes the transfer of myristate from CoAto proteins. NMT1 seems to be irreversible and is essential for fullexpression of the biologic activities of several N-myristoylated proteins, aswell as the alpha subunit of the signal-transducing guanine nucleotide-bindingprotein, G protein.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

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