N-Tetradecanoyl-DL-homoserine lactone
(Synonyms: N-十四烷酰-DL-高丝氨酸内酯,N-Myristoyl-DL-homoserine lactone) 目录号 : GC18593
N-tetradecanoyl-DL-homoserine lactone is a member of the N-acyl-homoserine lactone family.
Cas No.:98206-80-5
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >97.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
N-tetradecanoyl-DL-homoserine lactone is a member of the N-acyl-homoserine lactone family. N-acyl homoserine lactone (AHL) regulates gene expression in Gram-negative bacteria, such as Escherichia and Salmonella, which are involved in quorum sensing between bacteria and cell-to-cell communication. Some AHLs are potent chemical inducers of human immune cells (such as neutrophils).
N-tetradecanoyl-DL-homoserine lactone (C14-HSL) belongs to the class of homoserine lactones, including: N-heptanoyl-DL-homoserine lactone (C7HSL), N-octanoyl-homoserine lactone Lactone (N-C8-HSL), N-decanoyl-DL-homoserine lactone (N-C10-HSL), N-dodecanoyl-DL-homoserine lactone (C12-HSL), N- (3-oxodecanoyl) homoserine-L-lactone (3-oxo-C10 HSL), N-(3-oxododecanoyl) homoserine-L-lactone (3-oxo- C12-HSL), N-(3-oxotetradecanoyl)-L-homoserine lactone (3-oxo-C14-HSL, N-(3-hydroxydecanoyl)-L-homoserine lactone And N-(3-hydroxyoctanoyl)-L-homoserine lactones are involved in the process of bacterial quorum sensing. These N-acyl homoserine lactones are used to study the process and mechanism of bacterial quorum sensing.
| Cas No. | 98206-80-5 | SDF | |
| 别名 | N-十四烷酰-DL-高丝氨酸内酯,N-Myristoyl-DL-homoserine lactone | ||
| Canonical SMILES | CCCCCCCCCCCCCC(=O)NC1CCOC1=O | ||
| 分子式 | C18H33NO3 | 分子量 | 311.46 |
| 溶解度 | 储存条件 | Store at 2-8°C | |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 3.2107 mL | 16.0534 mL | 32.1069 mL |
| 5 mM | 0.6421 mL | 3.2107 mL | 6.4214 mL |
| 10 mM | 0.3211 mL | 1.6053 mL | 3.2107 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。