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Lanreotide

目录号 : GP21272

Lanreotide (BIM 23014) 是一种具有抗肿瘤活性的生长抑素类似物。

Lanreotide Chemical Structure

规格 价格 库存 购买数量
200μg
¥840.00
5-10工作日
1mg
¥2,030.00
5-10工作日
10mg
¥7,000.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

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产品描述

Lanreotide is an octapeptide, an analogue of a naturally occurring hormone, somatostatin.

Product Data

Purity Greater than 99.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. Source
Phycical Appearance Sterile Filtered White lyophilized (freeze-dried) powder. Shipping Condition Shipped at Room temp.
Solubility It is recommended to reconstitute the lyophilized Lanreotide in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Stability Lyophilized Lanreotide although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution Lanreotide should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Formulation The protein (1mg/ml) was lyophilized with 5mg manntitol and 0.04mg tween-80.

Introduction

Lanreotide is a peptide inhibitor of a number of endocrine, neuroendocrine, exocrine and paracrine functions. It shows good affinity for peripheral somatostatin receptors (anterior pituitary and pancreatic). In contrast, its affinity for central receptors is much lower. This profile confers a good specificity of action at the level of growth hormone and digestive hormone secretion. Lanreotide shows a much longer duration of action than natural somatostatin. In addition, its marked selectivity for the secretion of growth hormone, compared to that of insulin, makes it a suitable candidate for the treatment of acromegaly. By inhibiting the synthesis of thyroid stimulating hormone (TSH), lanreotide also normalised thyroid function of patients with thyrotrophin secreting adenomas in 50% (8/16) of the per-protocol population treated for 6 months. There was no significant reduction in the size of the adenoma. Furthermore, the inhibitory action of lanreotide on intestinal exocrine secretion, d

Stability

Lyophilized Lanreotide although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution Lanreotide should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.