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L-Serine-13C3 Sale

(Synonyms: L-丝氨酸-13C3,(-)-Serine-13C3; (S)-Serine-13C3) 目录号 : GC49417

An internal standard for the quantification of L-serine

L-Serine-13C3 Chemical Structure

Cas No.:201595-68-8

规格 价格 库存 购买数量
1mg
¥3,523.00
现货
5mg
¥7,601.00
现货
10mg
¥12,236.00
现货

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

L-Serine-13C3 is intended for use as an internal standard for the quantification of L-serine by GC- or LC-MS. L-Serine is a non-essential amino acid.1 It is produced from 3-phosphoglycerate in a multistep biosynthesis catalyzed by phosphoglycerate dehydrogenase (PGDH), phosphoserine aminotransferase (PSAT), and phosphoserine phosphatase (PSP). L-Serine can also be derived from dietary sources, as well as protein and phospholipid turnover. Defective L-serine biosynthesis is associated with neural tube defects and deoxysphingolipid accumulation in patients with Neu-Laxova syndrome, a rare disease characterized by a mutation in PGDH.1,2 Dysregulation of L-serine phosphorylation is associated with disease progression in patients with neurodegenerative diseases, including Alzheimer’s disease and amyotrophic lateral sclerosis.

1.Holm, L.J., and Buschard, K.L-serine: A neglected amino acid with a potential therapeutic role in diabetesAPMIS127(10)655-659(2019) 2.Metcalf, J.S., Dunlop, R.A., Powell, J.T., et al.L-serine: A naturally-occurring amino acid with therapeutic potentialNeurotox. Res.33(1)213-221(2018)

Chemical Properties

Cas No. 201595-68-8 SDF
别名 L-丝氨酸-13C3,(-)-Serine-13C3; (S)-Serine-13C3
Canonical SMILES O[13C]([13C@@H](N)[13CH2]O)=O
分子式 [13C]3H7O3 分子量 108.1
溶解度 Water: slightly, sonicated 储存条件 -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 9.2507 mL 46.2535 mL 92.5069 mL
5 mM 1.8501 mL 9.2507 mL 18.5014 mL
10 mM 0.9251 mL 4.6253 mL 9.2507 mL
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