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KLK8 Mouse

目录号 : GP21847

Kallikrein-8 Mouse Recombinant

KLK8 Mouse Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥72,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

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产品描述

KLK8 Mouse Recombinant produced in Sf9 is a single, glycosylated polypeptide chain containing 240 amino acids (29-260) and having a molecular mass of 26.5kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa). The KLK8 is fused to an 8 amino acid His-Tag at C-terminus and purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 95% as determined by SDS-PAGE. Source Sf9, Baculovirus cells.
Phycical Appearance Sterile Filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms Ovasin; PRSS19; TADG14; NRPN; NP; Kallikrein 8(Neuropsin/Ovasin) 2 EC 3.4.21.118; Kallikrein-8; Neuropsin; EC 3.4.21 61;HNP; HK8
Amino Acid Sequence QGSKILEGRE CIPHSQPWQA ALFQGERLIC GGVLVGDRWV LTAAHCKKQK YSVRLGDHSL QSRDQPEQEI QVAQSIQHPC YNNSNPEDHS HDIMLIRLQN SANLGDKVKP VQLANLCPKV GQKCIISGWG TVTSPQENFP NTLNCAEVKI YSQNKCERAY PGKITEGMVC AGSSNGADTC QGDSGGPLVC DGMLQGITSW GSDPCGKPEK PGVYTKICRY TTWIKKTMDN RDLEHHHHHH.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation KLK8 protein 0.5mg/ml is supplied in PBS, pH-7.4, and 10%Glycerol.

Introduction

Kallikrein-8is a serine protease which degrades various proteins such as casein,fibrinogen, kininogen, fibronectin and collagen type IV. Kallikrein-8 takespart in the formation and maturation of orphan and small synaptic boutons inthe Schaffer-collateral pathway, regulates Schaffer-collateral long-termpotentiation in the hippocampus and is essential for memory acquisition andsynaptic plasticity. Kallikrein-8 participates in the secondary phase ofpathogenesis following spinal cord injury and also takes part in skindesquamation and keratinocyte proliferation.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.