GLRX1 Yeast
目录号 : GP21684Glutaredoxin 1 Yeast Recombinant
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 90% as determined by SDS-PAGE. | Source | Escherichia Coli. |
Phycical Appearance | Sterile Filtered clear colorless solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | Thioltransferase; GRX; GLRX1; GRX1; GRX-1; GLRX-1; Glutathione-dependent oxidoreductase 1; Glutaredoxin 1. | ||
Stability | 1 week at 2-10°C . For long term store at -20 to -80°C . | ||
Formulation | Glutaredoxin solution contains 25mM Tris-HCl pH-7.5 & 0.01% Na Azide. |
GLRX1 has a glutathione-disulfide oxidoreductase activity in the presence of nadph and glutathione reductase. reduces low molecular weight disulfides and proteins.Glutaredoxin is a glutathione (GSH)-dependent hydrogen donor for ribonucleotide reductase and also catalyzes glutathione-disulfide oxidoreduction reactions in the presence of NADPH and glutathione reductase. GLRX1 is multifunctional enzyme with glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity. The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase. Required for resistance to reactive oxygen species (ROS) by directly reducing hydroperoxides and for the detoxification of ROS-mediated damage.
1 week at 2-10°C . For long term store at -20 to -80°C .