GH Chicken
目录号 : GP20331GH Chicken Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 99.0% as determined by:(a) Analysis by SDS-PAGE gel.(b) Analysis by SEC-HPLC. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
| Synonyms | GH1; GH; GHN; GH-N; hGH-N;Pituitary GH; GH 1; | ||
| Amino Acid Sequence | The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Thr-Phe-Pro-Ala. | ||
| Solubility | It is recommended to reconstitute the lyophilized GH Chicken Recombinant in sterile water or 0.4% NaHCO3 adjusted to pH 8-9, not less than 100µg/ml and not more than 3 mg/ml, which can then be further diluted to other aqueous solutions, preferably in presence of carrier protein. | ||
| Stability | Lyophilized GH Chicken although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution at > 0.1 mg/ml and filter sterilization GH can be stored at 4°C for several weeks. At lower concentration addition of a carrier protein (0.1% HSA or BSA) is recommended.Please prevent freeze-thaw cycles. | ||
| Biological Activity | GH Chicken Recombinantis fully biologically active in homologous assays and in PDF-P1 3B9 cells stably transfected with rabbit GH receptors. | ||
| Formulation | The protein was lyophilized from a concentrated (1mg/ml) solution with 0.3% NaHCO3 adjusted to pH 8. | ||
GH is a member of the prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at theGH locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five GHs, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in theGH locus. Mutations in or deletions of the gene lead toGH deficiency and short stature.
GH Chicken Recombinantis fully biologically active in homologous assays and in PDF-P1 3B9 cells stably transfected with rabbit GH receptors.
Lyophilized GH Chicken although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution at > 0.1 mg/ml and filter sterilization GH can be stored at 4°C for several weeks. At lower concentration addition of a carrier protein (0.1% HSA or BSA) is recommended.Please prevent freeze-thaw cycles.