CSF2RB Human
目录号 : GP20145GM-CSF Receptor Beta Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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CSF2RB Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 435 amino acids (17-443 a.a) and having a molecular mass of 49.7kDa. (Migrates at 40-57kDa on SDS-PAGE under reducing conditions). CSF2RB is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
| Purity | Greaterthan 95.0% as determined by SDS-PAGE. | Source | Sf9, Baculovirus cells. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | CSF2RB;ColonyStimulating Factor 2 Receptor; Beta; Low-Affinity (Granulocyte-Macrophage); GM-CSF/IL-3/IL-5Receptor Common Beta Subunit; CDw131; IL3RB; SMDP5; IL5RB; Interleukin 3Receptor/Granulocyte-Macrophage Colony Stimulating Factor 3 Receptor; Beta(High Affinity); Colony-Stimulating Factor-2 Receptor; Beta; Low-Affinity;GM-CSF/IL-3/IL-5 Receptor Common Beta-Chain; Cytokine Receptor CommonSubunit Beta; CD131 Antigen; CD131. | ||
| Amino Acid Sequence | WERSLAGAEE TIPLQTLRCY NDYTSHITCR WADTQDAQRL VNVTLIRRVNEDLLEPVSCD LSDDMPWSAC PHPRCVPRRC VIPCQSFVVT DVDYFSFQPD RPLGTRLTVT LTQHVQPPEPRDLQISTDQD HFLLTWSVAL GSPQSHWLSP GDLEFEVVYK RLQDSWEDAA ILLSNTSQAT LGPEHLMPSS TYVARVRTRL APGSRLSGRP SKWSPEVCWD SQPGDEAQPQNLECFFDGAA VLSCSWEVRK EVASSVSFGL FYKPSPDAGE EECSPVLREG LGSLHTRHHC QIPVPDPATHGQYIVSVQPR RAEKHIKSSV NIQMAPPSLN VTKDGDSYSL RWETMKMRYE HIDHTFEIQY RKDTATWKDS KTETLQNAHSMALPALEPST RYWARVRVRT SRTGYNGIWS EWSEARSWDT ESVLPMWLEH HHHHH. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. | ||
| Formulation | CSF2RB protein solution (0.5mg/ml)containing Phosphate Buffered Saline(pH7.4) and 10% glycerol. | ||
GM-CSF Receptor Beta, also known as CSF2RB is a member of the type I cytokine receptor family. CSF2RB is a high affinity receptor for interleukin-3, interleukin-5 as well as granulocyte-macrophage colony-stimulating factor. CSF2RB unique form of receptor assembly applies also to IL-3 and IL-5 receptors, providing a structural basis for understanding their activation mechanism which is essential for the development of therapeutics.
Store at 4°C if entire vial will be used within 2-4 weeks.