CRTAM Human
目录号 : GP23236Cytotoxic and Regulatory T Cell Molecule Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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CRTAM produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 278 amino acids (18-287 a.a.) and having a molecular mass of 31.0kDa. (Molecular size on SDS-PAGE will appear at approximately 40-57kDa).CRTAM is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
| Purity | Greater than 90.0% asdetermined by SDS-PAGE. | Source | Sf9,Insect cells. |
| Phycical Appearance | Sterilefiltered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Cytotoxic and Regulatory T Cell Molecule; Class I MHC Restricted T Cell Associated Molecule; Class-I MHC-Restricted T-Cell-Associated Molecule; Class-I MHC-Restricted T Cell Associated Molecule; Cytotoxic and Regulatory T-Cell Molecule; CD355 Antigen; CD355. | ||
| Amino Acid Sequence | SLTNHTETIT VEEGQTLTLKCVTSLRKNSS LQWLTPSGFT IFLNEYPALK NSKYQLLHHS ANQLSITVPN VTLQDEGVYK CLHYSDSVSTKEVKVIVLAT PFKPILEASV IRKQNGEEHV VLMCSTMRSK PPPQITWLLG NSMEVSGGTL HEFETDGKKCNTTSTLIIHT YGKNSTVDCI IRHRGLQGRK LVAPFRFEDL VTDEETASDA LERNSLSSQD PQQPTSTVSV TEDSSTSEIDKEEKEQTTQD PDLTTEANPQ YLGLARKKSG LEHHHHHH. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | CRTAM protein solution (1mg/ml) contains phosphate buffered saline (pH7.4) and 10% glycerol. | ||
Cytotoxic and Regulatory T Cell Molecule, also known as CRTAM belongs to the immunoglobulin superfamily which complies with the structural characteristics of the JAM family and is phylogenetically more closely related to nectin-like proteins. CRTAM is implicated in epithelial cell adhesion. Furthermore, CRTAM interacts with CADM1 as well as promotes natural killer (NK) cell cytotoxicity.
Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.