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Cephalomannine Sale

(Synonyms: 三尖杉宁碱) 目录号 : GN10780

A taxane diterpenoid

Cephalomannine Chemical Structure

Cas No.:71610-00-9

规格 价格 库存 购买数量
20mg
¥1,470.00
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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

Cephalomannine is a taxol derivative with antitumor, antiproliferative properties. IC50 value:Target: Cephalomannine is an active anti-cancer agent obtained from Taxus yunnanensis and has an antineoplastic effect on tumors found in mice. Cephalomannine is a chemotherapy drug that is given as a treatment for some types of cancer. Cephalomannine is most commonly used to treat non-small cell lung cancer.

References:
[1]. T. Grobosch, B. Schwarze, D. Stoecklein et al. Fatal poisoning with Taxus baccata. Quantification of Paclitaxel (taxol A), 10-Deacetyltaxol, Baccatin III, 10-Deacetylbaccatin III, Cephalomannine (taxol B), and 3,5-Dimethoxyphenol in Body Fluids by Liquid
[2]. Jing Zhang et al., Simultaneous Determination of 10-Deacetylbaccatin,Cephalomannine and Taxol in Different Parts of Taxus Media with Different Growth Years by UPLC. Applied Mechanics and Materials. 2011, 108, 326.
[3]. Chang Z, Guo N, Liu T, et al. Distribution and variation of paclitaxel and cephalomannine contents in wild Taxus cuspidata. Zhongguo Zhong Yao Za Zhi. 2011 Feb;36(3):294-8.
[4]. R Matesanz, J Rodríguez-Salarichs, B Pera, et al. Modulation of Microtubule Interprotofilament Interactions by Modified Taxanes. Biophysical Journal, 2011,101(12): 2970-2980.
[5]. Elena Riva, Martin Mattarella, Stella Borrelli, et al. Preparation of Fluorescent Tubulin Binders. ChemPlusChem. Early View (Online Version of Record published before inclusion in an issue)

Chemical Properties

Cas No. 71610-00-9 SDF
别名 三尖杉宁碱
Canonical SMILES CC=C(C)C(=O)NC(C1=CC=CC=C1)C(C(=O)OC2CC3(C(C4C(C(CC5C4(CO5)OC(=O)C)O)(C(=O)C(C(=C2C)C3(C)C)OC(=O)C)C)OC(=O)C6=CC=CC=C6)O)O
分子式 C45H53NO14 分子量 831.91
溶解度 DMF: 10mg/mL,DMSO: 15mg/mL,Ethanol: 15mg/mL,Ethanol:PBS (pH 7.2) (1:7): 0.12mg/mL 储存条件 4°C, protect from light
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

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1 mg 5 mg 10 mg
1 mM 1.2021 mL 6.0103 mL 12.0205 mL
5 mM 0.2404 mL 1.2021 mL 2.4041 mL
10 mM 0.1202 mL 0.601 mL 1.2021 mL
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