CDK1 Human
目录号 : GP22441细胞周期蛋白依赖性激酶 1 人类重组
Sample solution is provided at 25 µL, 10mM.
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CDK1 Human Recombinant produced in E.Coli is a single, non-glycosylatedpolypeptide chain containing 317 amino acids (1-297 a.a) and having a molecularmass of 36.2kDa.CDK1 is fused to a 20 aminoacid His-tag at N-terminus & purified by proprietary chromatographictechniques.
| Purity | Greater than 85.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Cyclin-Dependent Kinase 1; CDC2; Cell Division Cycle 2;G1 To S And G2 To M; Cell Division Control Protein 2 Homolog; Cell DivisionProtein Kinase 1; P34 Protein Kinase; P34CDC2; CDC28A; Cell Cycle ControllerCDC2; EC 2.7.11.22; EC 2.7.11.23; CDKN1; Cyclin-dependent kinase 1; CDK1. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSHMEDYTKIEKI GEGTYGVVYK GRHKTTGQVV AMKKIRLESE EEGVPSTAIR EISLLKELRH PNIVSLQDVLMQDSRLYLIF EFLSMDLKKY LDSIPPGQYM DSSLVKSYLY QILQGIVFCH SRRVLHRDLK PQNLLIDDKGTIKLADFGLA RAFGIPIRVY THEVVTLWYR SPEVLLGSAR YSTPVDIWSI GTIFAELATK KPLFHGDSEIDQLFRIFRAL GTPNNEVWPE VESLQDYKNT FPKWKPGSLA SHVKNLDENG LDLLSKMLIY DPAKRISGKMALNHPYFNDL DNQIKKM. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | CDK1protein solution (1mg/ml) containing 20mM Tris-HCl (pH8.0) and 10% glycerol. | ||
Cyclin-dependent kinase 1 (CDK1) plays a significant part in the control of the eukaryotic cell cycle through modulating the centrosome cycle in addition to mitotic onset; CDK1 promotes G2-M transition and regulates G1 progress and G1-S transition using association with multiple interphase cyclins. CDK1 is essential in higher cells for the entry into S-phase and mitosis.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.