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Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt) Sale

(Synonyms: Aβ (25-35)) 目录号 : GC42803

An 11-residue amyloid-β protein fragment

Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt) Chemical Structure

规格 价格 库存 购买数量
500μg
¥839.00
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1mg
¥1,593.00
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Sample solution is provided at 25 µL, 10mM.

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产品描述

Amyloid-β (25-35) (Aβ (25-35)) is an 11-residue fragment of the Aβ protein that retains the physical and biological characteristics of the full length peptide. It forms fibrils that react to thioflavin T and Congo red and are organized in a cross-β arrangement of β-strands similar to Aβ (1-40) and Aβ (1-42) fibrils. Aggregated Aβ (25-35) decreases the viability of rat adrenal PC12 cells. It also decreases the viability of primary rat cortical neurons at concentrations ranging from 1 nM to 30 μM. In vivo, intracerebral injection of Aβ (25-35) (20 nmol) in rats induces lesions of neuronal and tissue loss. Aggregated Aβ (25-35) administered intracerebroventricularly to rats induces learning and memory impairments in the Y-maze, novel object recognition, and contextual fear conditioning tests.

Chemical Properties

Cas No. SDF
别名 Aβ (25-35)
Canonical SMILES O=C([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CN)=O)CO)=O)CC(N)=O)=O)CCCCN)=O)=O)C)=O)[C@H](CC)C)N[C@H](C(NCC(N[C@H](C(N[C@@H](CCSC)C(O)=O)=O)CC(C)C)=O)=O)[C@H](CC)C.FC(F)(C(O)=O)F
分子式 C45H81N13O14S •XCF3COOH 分子量 1060.3
溶解度 Water: 1 mg/ml 储存条件 Store at -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 0.9431 mL 4.7156 mL 9.4313 mL
5 mM 0.1886 mL 0.9431 mL 1.8863 mL
10 mM 0.0943 mL 0.4716 mL 0.9431 mL
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