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AKT1 Human, Sf9

目录号 : GP22420

Protein Kinase B Alpha Human Recombinant, Sf9

AKT1 Human, Sf9 Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥72,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

AKT1 produced in Sf9 Baculovirus cells is a single,glycosylated polypeptide chain containing 488 amino acids (1-480a.a.) andhaving a molecular mass of 56.7kDa. (Molecular size on SDS-PAGE will appear atapproximately 50-70kDa).AKT1 is expressed with an 8 amino acid His tag atC-Terminus and purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 90.0% as determined by SDS-PAGE. Source Sf9,Baculovirus cells.
Phycical Appearance Sterile filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms V-Akt Murine Thymoma Viral Oncogene Homolog 1; ProteinKinase B Alpha; Proto-Oncogene C-Akt; RAC-PK-Alpha; EC 2.7.11.1; PKB Alpha;CWS6; PKB; RAC; RAC-Alpha Serine/Threonine-Protein Kinase; Rac Protein KinaseAlpha; Protein Kinase B; PKB-ALPHA; RAC-ALPHA; EC 2.7.11; AKT1m; PRKBA; AKT;RAC-alpha serine/threonine-protein kinase.
Amino Acid Sequence MSDVAIVKEG WLHKRGEYIK TWRPRYFLLK NDGTFIGYKE RPQDVDQREAPLNNFSVAQC QLMKTERPRP NTFIIRCLQW TTVIERTFHV ETPEEREEWT TAIQTVADGL KKQEEEEMDF RSGSPSDNSGAEEMEVSLAK PKHRVTMNEF EYLKLLGKGT FGKVILVKEK ATGRYYAMKILKKEVIVAKD EVAHTLTENR VLQNSRHPFL TALKYSFQTH DRLCFVMEYANGGELFFHLS RERVFSEDRA RFYGAEIVSA LDYLHSEKNV VYRDLKLENL MLDKDGHIKI TDFGLCKEGIKDGATMKTFC GTPEYLAPEV LEDNDYGRAV DWWGLGVVMY EMMCGRLPFY NQDHEKLFELILMEEIRFPR TLGPEAKSLL SGLLKKDPKQ RLGGGSEDAK EIMQHRFFAGIVWQHVYEKK LSPPFKPQVT SETDTRYFDE EFTAQMITIT PPDQDDSMEC VDSERRPHFP QFSYSASGTA LEHHHHHH.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation AKT1 protein solution (0. 5mg/ml) contains phosphatebuffered saline (pH7.4) and 20% glycerol.

Introduction

Akt1, also known as Akt or else protein kinase B (PKB) is an importantmolecule in mammaliancellular signaling. In humans, there are three genes inthe "Akt family": Akt1, Akt2, and Akt3. Moreover, these enzymes aremembers of the serine/threonine-specific protein kinase family (EC2.7.11.1). Akt1is involved in cellular survival pathways, by inhibiting apoptoticprocesses.Akt1 is also able to induce protein synthesis pathways, and is therefore a keysignaling protein in the cellular pathways which lead to skeletal musclehypertrophy, and general tissue growth. Since it can block apoptosis, andthereby promote cell survival, Akt1 has been implicated as a most importantfactor in numerous types of cancer. Akt (now also called Akt1) was at firstidentified as the oncogenein the transforming retrovirus, AKT8.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.