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4-hydroxy Nonenal Alkyne

(Synonyms: Click Tag 4HNE Alkyne) 目录号 : GC42411

4-HNE modified for click chemistry

4-hydroxy Nonenal Alkyne Chemical Structure

Cas No.:1011268-23-7

规格 价格 库存
100μg
¥742.00
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500μg
¥3,317.00
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1mg
¥5,892.00
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Sample solution is provided at 25 µL, 10mM.

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产品描述

4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid. It is considered a potential causal agent in numerous diseases, including chronic inflammation, neurodegenerative diseases, atherosclerosis, diabetes, and cancer, in part because it covalently modifies DNA and proteins resulting in genetic mutations and altered cell signaling, respectively. 4-HNE Alkyne is a form of 4-HNE with a terminal alkyne. Such terminal alkyne groups can be used in linking reactions, known as click chemistry, characterized by high dependability and specificity of azide-alkyne bioconjugation reactions. Click chemistry has only recently been applied to the study of oxidized lipids.

Chemical Properties

Cas No. 1011268-23-7 SDF
别名 Click Tag 4HNE Alkyne
Canonical SMILES [H]C(/C=C/C(O)CCCC#C)=O
分子式 C9H12O2 分子量 152.2
溶解度 DMF: 2.5 mg/ml,DMSO: 2 mg/ml,Ethanol: 12.5 mg/ml,PBS (pH 7.2): 5 mg/ml 储存条件 Store at -80°C; protect from light
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
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溶解性数据

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1 mg 5 mg 10 mg
1 mM 6.5703 mL 32.8515 mL 65.703 mL
5 mM 1.3141 mL 6.5703 mL 13.1406 mL
10 mM 0.657 mL 3.2852 mL 6.5703 mL
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