U2AF1 Human
目录号 : GP24933U2 Small Nuclear RNA Auxiliary Factor 1 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 90.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Splicing factor U2AF 35 kDa subunit; U2 auxiliary factor35 kDa subunit; U2 small nuclear RNA auxiliary factor 1; U2 snRNP auxiliaryfactor small subunit; U2AF35; U2AFBP; FP793; RNU2AF1; RN. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMAEYLAS IFGTEKDKVN CSFYFKIGAC RHGDRCSRLH NKPTFSQTILIQNIYRNPQN SAQTADGSHC AVSDVEMQEH YDEFFEEVFT EMEEKYGEVE EMNVCDNLGD HLVGNVYVKFRREEDAEKAV IDLNNRWFNG QPIHAELSPV TDFREACCRQ YEMGECTRGG FCNFMHLKPI SRELRRELYG RRRKKHRSRS RSRERRSRSRDRGRGGGGGG GGGGGGRERD RRRSRDRERS GRF | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | U2AF1 protein solution (1mg/ml) containing 20mM Tris-HClbuffer (pH 8.0), 0.4M UREA and 10% glycerol. | ||
U2AF1is a member of the splicing factor SR family. U2 auxiliary factor, comprising alarge and a smallsubunit, is a non-snRNP protein essential for the binding of U2 snRNP to thepre-mRNA branch site.U2AF1 is the small subunit which plays a vital role inboth constitutive and enhancer-dependent RNA splicing by directly mediating interactions betweenthe large subunit and proteins bound to the enhancers. U2 small nuclear RNAauxiliary factor 1 (U2AF1) is a protein-coding gene. Among the diseases whichare associated with U2AF1:Myoclonus Epilepsy and progressive Myoclonus Epilepsy.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.