TYRP1 Human
目录号 : GP24930Tyrosinase Related Protein 1 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 85.0% as determined by SDS-PAGE. | Source | Sf9,Baculovirus cells. |
| Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Tyrosinase Related Protein 1; Tyrosinase-Related Protein1; Melanoma Antigen Gp75; Glycoprotein 75; DHICA Oxidase; Catalase B; CAS2; TRP1;TYRP; TRP; 5;6-Dihydroxyindole-2-Carboxylic Acid Oxidase; EC 1.14.18.1; EC1.14.18.-; EC 1.14.18; B-PROTEIN; TRP-1; TYRRP; CATB; GP75; OCA3; 5;6-dihydroxyindole-2-carboxylicacid oxidase. | ||
| Amino Acid Sequence | ADLQFPRQCATVEALRSGMC CPDLSPVSGP GTDRCGSSSG RGRCEAVTAD SRPHSPQYPH DGRDDREVWP LRFFNRTCHCNGNFSGHNCG TCRPGWRGAA CDQRVLIVRR NLLDLSKEEK NHFVRALDMA KRTTHPLFVI ATRRSEEILGPDGNTPQFEN ISIYNYFVWT HYYSVKKTFLGVGQESFGEV DFSHEGPAFL TWHRYHLLRL EKDMQEMLQE PSFSLPYWNFATGKNVCDIC TDDLMGSRSN FDSTLISPNS VFSQWRVVCD SLEDYDTLGT LCNSTEDGPI RRNPAGNVARPMVQRLPEPQ DVAQCLEVGL FDTPPFYSNS TNSFRNTVEG YSDPTGKYDP AVRSLHNLAHLFLNGTGGQT HLSPNDPIFVLLHTFTDAVF DEWLRRYNAD ISTFPLENAP IGHNRQYNMV PFWPPVTNTE MFVTAPDNLG YTYEIQWPSR EFSVPEHHHHHH. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | TYRP1 protein solution (0.25mg/ml) containing PhosphateBuffered Saline (pH 7.4) and 10% glycerol. | ||
TYRP1,also known as 5, 6-dihydroxyindole-2-carboxylic acid oxidase, is a melanosomalenzyme which is a member of the tyrosinase family and takes a significant partin the melanin biosynthetic pathway. TYRP1 is a melanocyte-specificgene which is involved in eumelanin synthesis. Furthermore, TYRP1 is implicatedin the oxidation of 5,6-dihydroxyindole-2-carboxylicacid-DHICA into indole-5,6-quinone-2-carboxylic acid. TYRP1 is regulated by themicrophthalmia-associated transcriptionfactor-MITF.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.