TROVE2 Human
目录号 : GP24896TROVE 域家族成员 2 人类重组
Sample solution is provided at 25 µL, 10mM.
RO-60 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain having a molecular mass of 60kDa. RO60 is fused to a 6 amino acid His-Tag at C-terminus and purified by proprietary chromatographic techniques.
Purity | Greater than 90.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | 60 kDa SS-A/Ro ribonucleoprotein; 60 kDa ribonucleoprotein Ro; RoRNP; 60 kDa Ro protein; Ro 60 kDa autoantigen; TROVE domain family member 2; Sjoegren syndrome type A antigen; SS-A; Sjoegren syndrome antigen A2; TROVE2; RO60; SSA2; RO-60. | ||
Stability | RO-60 although stable at 4°C for 3 weeks, should be stored below -18°C . Please prevent freeze-thaw cycles. | ||
Formulation | The protein solution contains 6M Urea, 500mM NaCl, 500mM imidazole and 10mM Tris pH-6. |
Ro 60 kDa autoantigen is an RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. SSA2 may stabilize these RNAs from degradation. Sera taken from patients with Systemic Lupus Erythematosus (SLE) often contains antibodies that react with the normal cellular SSA2 protein as if this antigen was foreign.
RO-60 although stable at 4°C for 3 weeks, should be stored below -18°C . Please prevent freeze-thaw cycles.