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TRIM21 Human Biotin

目录号 : GP24881

Tripartite Motif Containing 21 (RO52) Human Recombinant, Biotinylated

TRIM21 Human Biotin Chemical Structure

规格 价格 库存 购买数量
50μg
¥8,400.00
5-10工作日
100μg
¥12,600.00
5-10工作日
1mg
¥72,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

TRIM21 Human Recombinant, Biotin produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 52kDa.TRIM21 is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 80% as determined by SDS-PAGE. Source Sf9 insect cells.
Phycical Appearance Sterile Filtered clear solution. Shipping Condition Shipped with Ice Packs.
Synonyms 52 kDa Ro protein; Sjoegren syndrome type A antigen; SS-A; Ro(SS-A); 52 kDa ribonucleoprotein autoantigen Ro/SS-A; Tripartite motif-containing protein 21; RING finger protein 81; TRIM21; RNF81; RO52; SSA1; SSA; RO-52.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Avoid multiple freeze-thaw cycles.
Formulation TRIM21 solution is supplied in 20mM HEPES pH-7.6, 0.01mM EDTA and 0.02% SDS.

Introduction

TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The 52 kDa Ro protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. Ro/SSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Ribonucleoprotein particle is composed of a single polypeptide and one of four small RNA molecules. The RoSSA is present in all mammalian cells studied but has no known function. At least 2 isoforms are present in nucleated and red blood cells, and tissue specific differences in Ro/SSA proteins were identified.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Avoid multiple freeze-thaw cycles.