TNF a Human, Sf9
目录号 : GP20967Tumor Necrosis Factor-alpha Human Recombinant, Sf9
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 90.0% as determined bySDS-PAGE. | Source | Sf9,Baculovirus cells. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Tumor Necrosis Factor; TNFA; Tumor Necrosis Factor LigandSuperfamily Member 2; Cachectin; TNF-Alpha; TNFSF2; TNF-A; Tumor Necrosis Factor(TNF Superfamily; Member 2); Tumor Necrosis Factor-Alpha; TNF;Macrophage-Derived; TNF; Monocyte-Derived; TNF Superfamily; APC1 Protein;Member 2; DIF; Tumor necrosis factor. | ||
| Amino Acid Sequence | VRSSSRTPSD KPVAHVVANP QAEGQLQWLN RRANALLANG VELRDNQLVVPSEGLYLIYS QVLFKGQGCP STHVLLTHTI SRIAVSYQTK VNLLSAIKSP CQRETPEGAE AKPWYEPIYLGGVFQLEKGD RLSAEINRPD YLDFAESGQV YFGIIALHHH HHH. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. | ||
| Biological Activity | Measured in a cytotoxicity assay using L929 mouse fibrosarcomacells in the presence of the metabolic inhibitor actinomycin D.The ED50 for this effect is б▄ 0.2 ng/ml. | ||
| Formulation | TNF a protein solution (1mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 10% glycerol. | ||
Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages.TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesis and viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF's primary role is in the regulation of immune cells.Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases- autoimmune diseases, insulin resistance, and cancer.
Measured in a cytotoxicity assay using L929 mouse fibrosarcomacells in the presence of the metabolic inhibitor actinomycin D.The ED50 for this effect is б▄ 0.2 ng/ml.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.