SNAI1 Human
目录号 : GP24620Snail Family Zinc Finger 1 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greaterthan 85% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Snail Family Zinc Finger 1; ProteinSna; Protein Snail Homolog 1; SNAH; Snail 1 (Drosophila Homolog); Zinc FingerProtein; Snail Homolog 1 (Drosophila); SLUGH2; SNA; SNAIL; SNAIL1; dJ710H13.1; Snail1 Homolog; Snail 1 Zinc Finger Protein; Snail 1; Zinc Finger Protein; SnailHomolog 1; Zinc Finger Protein SNAI1. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMPRSFLV RKPSDPNRKP NYSELQDSNP EFTFQQPYDQ AHLLAAIPPPEILNPTASLP MLIWDSVLAP QAQPIAWASL RLQESPRVAE LTSLSDEDSG KGSQPPSPPS PAPSSFSSTSVSSLEAEAYA AFPGLGQVPK QLAQLSEAKD LQARKAFNCK YCNKEYLSLG ALKMHIRSHT LPCVCGTCGK AFSRPWLLQG HVRTHTGEKPFSCPHCSRAF ADRSNLRAHL QTHSDVKKYQ CQACARTFSR MSLLHKHQES GCSGCPR | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. | ||
| Formulation | SNAI1 protein solution (1mg/ml) containing 20mM Tris-HClbuffer (pH 8.0), 0.4M urea and 10% glycerol. | ||
Snailhomolog 1 (SNAI1) is involved in induction of the epithelial to mesenchymaltransition (EMT), formation and maintenance of embryonic mesoderm, growtharrest, survival and cell migration. SNAI1 binds to 3 E-boxes of the E-cadheringene promoterand represses its transcription. The nuclear protein encoded by SNAI1 isstructurally identical to the Drosophila snail protein, and is considered aswell to be vital for mesoderm formation in the developing embryo. At least twovariants of a similar processed pseudogene have been found on chromosome 2. Among the diseases associated with SNAI1 are waardenburgsyndrome type iid, and inappropriate adh syndrome.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.