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SCO1 Human

目录号 : GP24503

SCO Cytochrome Oxidase Deficient Homolog 1 Human Recombinant

SCO1 Human Chemical Structure

规格 价格 库存 购买数量
5μg
¥840.00
5-10工作日
20μg
¥2,030.00
5-10工作日
1mg
¥37,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

SCO1 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 179 amino acids (132-301 a.a) andhaving a molecular mass of 20.5kDa.

Product Data

Purity Greater than 95% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms SCO1 Cytochrome C Oxidase Assembly Protein; SCOD1; SCO(Cytochrome Oxidase Deficient; Yeast) Homolog 1; SCO Cytochrome OxidaseDeficient Homolog 1 (Yeast); SCO Cytochrome Oxidase Deficient Homolog 1; ProteinSCO1 Homolog; Mitochondrial; SCOD1; Protein SCO1 homolog; mitochondrial.
Amino Acid Sequence MGKPLLGGPF SLTTHTGERK TDKDYLGQWL LIYFGFTHCP DVCPEELEKMIQVVDEIDSI TTLPDLTPLF ISIDPERDTK EAIANYVKEF SPKLVGLTGT REEVDQVARA YRVYYSPGPKDEDEDYIVDH TIIMYLIGPD GEFLDYFGQN KRKGEIAASI ATHMRPYRKK SLEHHHHHH.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation SCO1 protein solution (1mg/ml) containing Phosphatebuffered saline (pH7.4), 10% glycerol and 1mM DTT.

Introduction

SCO Cytochrome Oxidase Deficient Homolog 1, also known as SCO1 is amember of the SCO1/2 family. Mammalian cytochrome c oxidase (COX) catalyzes thetransfer of reducing equivalents from cytochrome c to molecular oxygen andpumps protons across the inner mitochondrial membrane. Furthermore, in yeast, tworelated COX assembly genes, SCO1 & SCO2 which are synthesis of cytochrome coxidase, enable subunits 1 as well as 2 to be incorporated into theholoprotein. This gene is the human homolog to the yeast SCO1 gene. Among the diseasesassociated with SCO1 are hepatic failure, early-onset, neurologic disorder dueto cytochrome c oxidase deficiency and fatal infantile cytochrome c oxidasedeficiency.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

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