Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Products for Endogenous Metabolite

Cat.No. 产品名称 Information
GC15649 Substance P
P物质; Neurokinin P
An endogenous NK₁ receptor agonist
GC11064 Spermine tetrahydrochloride
精胺四盐酸盐
A natural polyamine
GC16831 Agmatine sulfate
胍基丁胺；硫酸胍基丁胺；硫酸鲱精胺；胍基丁胺硫酸盐
A polyamine metabolite
GC17591 D-erythro-Sphingosine (synthetic)
鞘氨醇; Erythrosphingosine; erythro-C18-Sphingosine; trans-4-Sphingenine
D-erythro-sphingosine (Erythrosphingosine) 是一种非常有效的 p32 激酶激活剂，EC50 值为 8μM。
GC13890 (±)-Palmitoylcarnitine chloride
C16:0 Carnitine, CAR 16:0, DL-Carnitine hexadecanoyl ester, DL-Carnitine palmitoyl ester, Hexadecanoyl-DL-carnitine, DL-Hexadecanoylcarnitine, NSC 628323, DL-Palmitoylcarnitine
A long-chain acylcarnitine with intracellular and extracellular roles
GC14301 Spaglumic acid
异冬谷酸,N-Acetylaspartylglutamic acid
A peptide neurotransmitter
GC10123 O-Phospho-L-serine
L-O-磷酸丝氨酸,L-Serine O-phosphate; L-SOP
A glutamate receptor agonist
GC14547 Quinolinic acid
喹啉酸
An excitotoxic agonist at NMDA receptors
GC17823 L-Cysteinesulfinic acid
L-半胱氨酸亚磺酸
L-半胱氨酸亚磺酸是几种大鼠代谢型谷氨酸受体 (mGluR) 的有效激动剂，对 mGluR1、mGluR5、mGluR2、mGluR4、mGluR6 和 mGluR8 的 pEC50 分别为 3.92、4.6、3.9、2.7、4.0 和 3.94 .
GC14943 Hypotaurine
亚牛磺酸; 2-Aminoethanesulfinic acid
An endogenous inhibitory amino acid and antioxidant
GC10897 2'-Deoxyguanosine
2′-脱氧鸟苷; Deoxyguanosine; Guanine deoxyriboside
2'-脱氧鸟苷（Deoxyguanosine）由嘌呤核苷鸟嘌呤通过其N9氮与脱氧核糖的C1碳相连。
GC14055 Vanillin
香兰素; p-Vanillin; m-Methoxy-p-hydroxybenzaldehyde; p-Hydroxy-m-methoxybenzaldehyde
An Analytical Reference Standard
GC17902 Inosine
肌苷
A purine nucleoside
GC10199 Hypoxanthine
次黄嘌呤; Purin-6-ol; Sarcine
An endogenous purine derivative
GC10829 Heparin
肝素
肝素是一种高度硫酸化的糖胺聚糖，被广泛用作注射用抗凝剂，在任何已知生物分子中具有最高的负电荷密度。
GC12917 Acetaminophen
对乙酰氨基酚; Paracetamol; 4-Acetamidophenol; 4'-Hydroxyacetanilide

An analgesic and antipyretic compound
GC11344 Eicosapentaenoic Acid
二十碳五烯酸; EPA; Timnodonic acid
Eicosapentaenoic Acid（EPA）二十碳五烯酸是一种具有口服活性的omega-3（ω-3）长链多不饱和脂肪酸（PUFA），是前列腺素3、血栓素3和白三烯5类二十烷酸的前体。
GC10977 Methylcobalamin
甲钴胺; CH3-B12
An analog of vitamin B₁₂
GC11272 Phenylephrine HCl
盐酸去氧肾上腺素; (R)-(-)-Phenylephrine hydrochloride; L-Phenylephrine hydrochloride
Phenylephrine HCl（盐酸去氧肾上腺素）是一种选择性的α1-肾上腺素能受体激动剂。
GC13742 Uridine
尿苷; β-Uridine
A pyrimidine nucleoside
GC14142 Acetylcholine Chloride
氯化乙酰胆碱; ACh chloride
A neurotransmitter
GC18002 Vitamin B12
维生素B12; Cyanocobalamin
A corrinoid vitamin
GC12256 D-Mannitol
D-甘露醇 ; Mannitol; Mannite
An Analytical Reference Standard
GC14573 Xylose
DL-木糖; (±)-Xylos
木糖是有机合成的中间体。
GC12974 Medroxyprogesterone acetate
醋酸甲羟孕酮; Medroxyprogesterone 17-acetate; Farlutin
Medroxyprogesterone acetate（MPA）是一种人工合成的孕激素。
GC17216 NAD+
烟酰胺腺嘌呤双核苷酸
NAD+是一种转递氢离子的辅酶，参与许多酶促反应，由核糖基烟酰胺5'-二磷酸通过焦磷酸键与5'-磷酸腺苷偶联组成。
GC15405 Riboflavin (Vitamin B2)
维生素B2,Vitamin B2; E101
核黄素（维生素 B2）是一种易于吸收的微量营养素，在维持人类和其他动物的健康方面发挥着关键作用。
GC14098 Menadione
维生素K3; Vitamin K3
A provitamin
GC11029 Isoprenaline HCl
盐酸异丙肾上腺素; Isoproterenol hydrochloride

A β₁- and β₂-AR agonist
GC17278 Adenine sulfate
硫酸腺嘌呤; 6-Aminopurine hemisulfate; Vitamin B4 hemisulfate
A purine base
GC15509 Uracil
尿嘧啶
A pyrimidine nucleoside
GC15184 Taurine
牛磺酸; 2-Aminoethanesulfonic acid
A sulfur-containing amino acid
GC12715 Synephrine HCl
辛弗林盐酸盐; Oxedrine hydrochloride
An alkaloid
GC10278 Sucralose
三氯蔗糖; E955; Trichlorosucrose
A synthetic disaccharide and non-caloric sweetener
GC15502 Gluconate sodium
葡萄糖酸钠; D-Gluconic acid sodium salt; Sodium D-gluconate; D-Gluconate sodium salt
葡萄糖酸钠（D-葡萄糖酸钠盐）是普通钢在模拟冷却水中的缓蚀阻垢剂。
GC14843 Serotonin HCl
5-羟基色胺盐酸盐; 5-Hydroxytryptamine hydrochloride; 5-HT hydrochloride

Serotonin HCl是一种神经递质，是介导人体多种中枢和外周功能的关键信使。
GC15755 Ribitol
核糖醇; Adonitol; Adonite
A pentose sugar alcohol
GC17393 Pyridoxine HCl
吡哆醇盐酸盐; Pyridoxol hydrochloride; Vitamin B6 hydrochloride
A 4-methanol form of vitamin B₆
GC10675 (+,-)-Octopamine HCl
章胺盐酸盐; (±)-p-Octopamine hydrochloride
An endogenous biogenic amine
GC12182 Estriol
雌三醇; Oestriol
An estradiol metabolite produced during pregnancy
GC18075 Erythritol
赤藓糖醇
赤藓糖醇是一种糖醇，天然存在于各种食物中（例如。
GC16292 Equol
(±)-雌马酚
An estrogen receptor agonist
GC13072 Epiandrosterone
表雄酮; 3β-Androsterone; trans-Androsterone; iso-Androsterone
An Analytical Reference Standard
GC12349 Deoxycorticosterone acetate
醋酸去氧皮质酮; 11-Deoxycorticosterone acetate; DOC acetate; Cortexone acetate
A corticosteroid
GC13502 Cysteamine HCl
半胱胺盐酸盐; 2-Aminoethanethiol hydrochloride; 2-Mercaptoethylamine hydrochloride
A radioprotective aminothiol
GC11872 Creatinine
肌酸酐; NSC13123
The end product of the creatine-creatine phosphate energy shuttle
GC17398 Cholesterol
胆固醇

A sterol
GC11843 Azaguanine-8
8-氮鸟嘌呤; 8-AG
Azaguanine-8 是一种嘌呤类似物，具有抗肿瘤活性。 Azaguanine-8 起抗代谢物的作用，很容易与核糖核酸结合，干扰正常的生物合成途径，从而抑制细胞生长。
GC16443 4-Aminohippuric Acid
对氨基马尿酸; p-Aminohippuric acid
A substrate for OAT1, NPT1, and MDR2
GC17829 1-Hexadecanol
鲸蜡醇
鲸蜡醇（1-Hexadecanol）是一种合成的固体脂肪醇和非离子表面活性剂，是一种亲脂性底物，鲸蜡醇在药物制剂中用作乳化剂。