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XAO (xanthine oxidase), also known as xanthine oxidoreductase and xanthine dehydrogenase, catalyzes the oxidation of hypoxanthine to xanthine and the oxidation of xanthine to uric acid. It is an evolutionarily conserved enzymes that play a central role in purine catabolism.

  1. Cat.No. 产品名称 Information
  2. GC15322 Allopurinol 别嘌醇是一种有效的口服黄嘌呤氧化酶抑制剂,IC50 值为 0.2-50 μM。
  3. GC16319 Febuxostat Febuxostat (TEI 6720) 是一种有效的、选择性的、非嘌呤黄嘌呤氧化酶 (XO) 抑制剂,Ki 值为 0.6 nM。
  4. GC10827 Oxipurinol Oxipurinol (Oxipurinol) 是别嘌醇的主要活性代谢物,是黄嘌呤氧化酶的抑制剂。
  5. GC16127 Topiroxostat Topiroxostat (FYX-051) 是一种有效且具有口服活性的黄嘌呤氧化还原酶 (XOR) 抑制剂,IC50 值为 5.3 nM,Ki 值为 5.7 nM。

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