Gutathione S-transferase(谷胱甘肽S-转移酶)

GSTs (Glutathione s-transferases)is a detoxification enzyme that catalyze the binding of electrophilic substrates to glutathione. They involved in removal of ROS, inhibition of Jun kinase and can conjugate non-catalytically to various ligands.

Cat.No. 产品名称 Information
GC64919 AZD9898 AZD9898 是一种口服有效的白三烯-C4 合成酶 (LTC4S) 抑制剂，IC50 值为 0.28 nM。AZD9898 减轻GABA 结合和肝毒性信号。AZD9898 可用于哮喘的研究。
GC35727 Coniferyl ferulate A monolignal conjugate with diverse biological activities
GC35759 Curzerene Curzerene, a sesquiterpene isolated from the rhizome of Curculigo orchioides Gaertn with anti-cancer activity, inhibits glutathione S-transferase A1 (GSTA1) mRNA and protein expression and induces cell apoptosis.
GC10519 Ethacrynic acid - d5 An internal standard for the quantification of ethacrynic acid
GC18095 Ezatiostat An inhibitor of GSTP1-1
GC13409 Ezatiostat hydrochloride An inhibitor of GSTP1-1
GC33342 GSTO-IN-2 GSTO-IN-2是一种谷胱甘肽S-转移酶(glutathioneS-transferase)抑制剂，对于GSTA2，GSTM1和GSTP1-1的IC50值分别为3.6，16.3，1.4μM。
GC32971 GSTO1-IN-1 GSTO1-IN-1是一种有效的谷胱甘肽S-转移酶omega1(GSTO1)抑制剂，IC50为31nM。
GC17287 Iberin
A natural isothiocyanate
GC63518 LAS17
LAS17 是一种强效的，不可逆的，选择性谷胱甘肽 S-转移酶 Pi (GSTP1) 抑制剂。LAS17 抑制 GSTP1 活性，IC50 为 0.5 µM.
GC44882 Seneciphylline An alkaloid with diverse biological activities
GC65438 TK05 TK05 是一种有效选择性的白三烯 C4 合成酶 (LTC4S) 抑制剂，其 IC50 值为 95 nM。
GC30647 TLK117 (TER117) TLK117 (TER117) 是 TLK199 的活性代谢物，选择性抑制谷胱甘肽 S-转移酶 P1-1 (GSTP1-1)，Ki 为 0.4 ⋼M 用于 GSTP。