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Home >> Signaling Pathways >> Others >> Glucosidase

Glucosidase(葡萄糖苷酶)

Glucosidases are glycoside hydrolase enzymes.

α-glucosidase is a glucosidase located in the brush border of the small intestine that acts upon α(1→4) bonds. α-Glucosidase inhibitor is a new type of antidiabetics. By reducing the postprandial blood sugar concentration, it can effectively control the blood sugar levels, thereby reducing the occurrence of diabetic complications.

β-glucosidase catalyzes the hydrolysis of the glycosidic bonds to terminal non-reducing residues in β-D-glucosides and oligosaccharides, with release of glucose. β-Glucosidase has attracted substantial attention in the scientific community because of its pivotal role in cellulose degradation, glycoside transformation and many other industrial processes. β-glucosidases catalyze the final step of cellulose hydrolysis and are essential in cellulose degradation.

  1. Cat.No. 产品名称 Information
  2. GC62551 β-Hydroxypropiovanillone
  3. GC39795 (+)-Afzelechin
  4. GN10317 1-Deoxynojirimycin An iminosugar with diverse biological activities
  5. GC41992 1-Deoxynojirimycin (hydrochloride) An iminosugar with diverse biological activities
  6. GC30277 4',5-Dihydroxyflavone 4',5-Dihydroxyflavone inhibits soybean LOX-1 and yeast α-glucosidase.
  7. GC35553 Brevifolincarboxylic acid A phenol with anticancer and anti-inflammatory activities
  8. GC39233 Butyl isobutyl phthalate Butyl isobutyl phthalate (BIP), isolated from the rhizoid of Laminaria japonica, is a non-competitive inhibitor of α-glucosidase with IC50 of 38 μM. Butyl isobutyl phthalate displays a significant hypoglycemic effect and has the potential for diabetes treatment.
  9. GC38279 Cedryl acetate Cedryl Acetate (Cedrol acetate, Cedranyl acetate), an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions. Cedryl acetate exhibits α-glucosidase inhibitory activity.
  10. GC31580 Cefetrizole
  11. GC32191 Celgosivir (MBI 3253)
  12. GC32074 Celgosivir hydrochloride (MBI 3253 (hydrochloride))
  13. GC60706 Chrysophanol triglucoside
  14. GC18058 Conduritol B epoxide An irreversible inhibitor of glucocerebrosidase
  15. GC60802 Eleutherol
  16. GC62984 Ganoderic acid Y
  17. GC64202 Ganoderlactone D
  18. GC38046 Gitogenin A sapogenin with enzyme inhibitory and hormone-releasing activities
  19. GC36165 Glycyrrhisoflavone
  20. GC36347 Isotanshinone I
  21. GC36375 Kaempferol 3-O-gentiobioside
  22. GC64519 Kaempferol-3,7-di-O-β-glucoside
  23. GC61635 Kaempferol-7-O-rhamnoside
  24. GN10551 Licochalcone C Licochalcone C 可以抑制 α-葡萄糖苷酶，对 α-葡萄糖苷酶和蛋白酪氨酸磷酸酶 1B (PTP1B) 的 IC50 值分别为 <100 nM 和 92.43 μM。
  25. GC64507 ML198 ML198 is a novel activator of glucocerebrosidase (GCase) with an IC50 of 0.4 μM and does not inhibit the enzyme's action, but can facilitate its translocation to the lysosome.
  26. GC63442 N-Caffeoyl O-methyltyramine N-Caffeoyl O-methyltyramine is a class of alkaloid isolated from Cuscuta reflexa with strong inhibitory activity against α-glucosidase with IC50 of 103.58 μM.
  27. GC30637 N-Methylmoranoline (MOR 14)

    An inhibitor of glycoprotein processing and α-glucosidases
  28. GC61697 Naringinase
  29. GC63099 NCGC00092410
  30. GC67983 Norathyriol
  31. GN10114 Oroxin A A flavonoid glycoside
  32. GC65271 p-Hydroxyphenethyl trans-ferulate
  33. GC38995 Panasenoside
  34. GN10011 Rebaudioside A A natural non-caloric sweetener
  35. GC61242 Resveratroloside
  36. GC34835 Terphenyllin

    A fungal metabolite with antibacterial properties
  37. GC18007 Voglibose An α-glucosidase inhibitor

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