BCRP(乳腺癌耐药蛋白)

BCRP(breast cancer resistance protein), also called ABCG2 (ATP-binding cassette subfamily G member 2) is expressed in MDR (multi-drug resistance) diverse cancer cells. It protects cell from toxic xenobiotic substance in intestine, biliary tract, placenta, blood-testis barrier and blood-brain barriers.

Cat.No. 产品名称 Information
GC33099 BCRP-IN-1
GC17215 Elacridar An inhibitor of MRP-1 and BCRP
GC36034 FD 12-9
GC10874 Fumitremorgin C Inhibitor of BCRP multidrug transporter
GC12711 Ko 143 Inhibitor of the multidrug transporter BCRP
GC14688 KS 176 A selective BCRP inhibitor
GC38129 ML753286
GC18163 YHO-13177 YHO-13177 是一种有效的特异性 BCRP 抑制剂；增强了 SN-38 在癌细胞中的细胞毒性，并且对 MDR1 转导的人白血病 K562 细胞中 P-糖蛋白介导的紫杉醇抗性没有影响。
GC32114 YHO-13351
GC33056 YHO-13351 free base
GC32593 Zamicastat (BIA 5-1058)