PGE synthase(PGE合酶)
Prostagladin E synthase catalzyes the oxidoreduction of PGHS (prostaglandin endoperoxde h2) into PGE2(prostaglandin E2). It is implicated in physiological conditions such as fever, pain and arthritis etc.
- Cat.No. 产品名称 Information
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GC15058
Benzydamine HCl
An Analytical Reference Standard
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GC17707
Bismuth Subsalicylate
Bismuth Subsalicylate 是一种有效的、具有口服活性的抗酸剂和止泻剂。
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GC40352
Cafestol
A natural diterpene which increases serum cholesterol
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GC18904
CAY10678
A mPGES-1 inhibitor
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GC38431
Dehydroevodiamine
An alkaloid with diverse biological activities
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GC38678
Ethyl Caffeate
Ethyl caffeate, a naturally occurring compound found in Bidens pilosa, suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2 and PGE2 in vitro.
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GC16880
Flurbiprofen
A non-selective COX inhibitor
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GC14633
HPGDS inhibitor 1
An inhibitor H-PGDS
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GC36254
HPGDS inhibitor 2
HPGDS inhibitor 2 是一种高效选择性的造血前列腺素 D 合成酶 (H-PGDS) 抑制剂,IC50 值为 9.9 nM。
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GC10564
HQL 79
A selective HPGD synthase inhibitor
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GC36463
Limaprost
A stable, potent analog of PGE1
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GC16607
Mesalamine
An NSAID and active metabolite of sulfasalazine, balsalazide, and olsalazine
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GC11743
MF63
A potent, selective, and orally active mPGES-1 inhibitor
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GC36649
mPGES1-IN-3
mPGES1-IN-3 (Compound 17d) 是一种有效的选择性微粒体前列腺素 E2 合成酶-1 (mPGES-1) 抑制剂,抑制 mPGES-1 酶,IC50 为 8 nM,抑制 A549 细胞,IC50 为 16.24 nM。
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GC18700
PF-4693627
An orally bioavailable mPGES-1 inhibitor
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GC32038
PGS-IN-1 (KME-4)
PGS-IN-1 (KME-4) 是一种有效的前列腺素合成酶 (PGS) 抑制剂,IC50 为 0.28 μM;也抑制 5-脂氧合酶,IC50 为 1.05 μM.
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GC11670
Pranoprofen
An NSAID and COX-1 inhibitor
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GC12330
SAR191801
SAR191801 是一种 hPGDS 抑制剂,在荧光偏振试验或 EIA 试验中的 IC50 为 12 nM。
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GN10280
Sinensetin
An anti-inflammatory flavone
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GC14438
Suprofen
A non-selective NSAID
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GC50101
TFC 007
An H-PGDS inhibitor
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GC70119
Vipoglanstat
Vipoglanstat (BI 1029539),甲酰胺,是一种有效的,选择性的,非肽人前列腺素 E 合成酶 1 (mPGES-1) 小分子抑制剂,具有口服活性。Vipoglanstat 也具有抗炎活性。
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GC63394
Zaloglanstat
Zaloglanstat (ISC-27864) 是 mPGES-1 的抑制剂,可用于哮喘、骨关节炎、类风湿性关节炎、急性或慢性疼痛和神经退行性疾病等的研究。
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GC31687
Zomepirac sodium salt (McN-2783-21-98)
Zomepirac sodium salt (McN-2783-21-98) (McN-2783-21-98) 是一种有效的前列腺素生物合成抑制剂。