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Home >> Signaling Pathways >> GPCR/G protein >> 5-HT Receptor

5-HT Receptor(5-羟色胺受体)

5-HT receptor (5-hydroxytryptamine receptors) is a group of GPCRs (G protein-coupled receptors) and LGICs (ligand-gated ion channels) found in the central and peripheral nervous systems.

Products for  5-HT Receptor

  1. Cat.No. 产品名称 Information
  2. GC12744 NPS ALX Compound 4a dihydrochloride NPS ALX Compound 4a dihydrochloride 是一种有效的选择性 5-hydroxytryptamine6 (5-HT6) 受体拮抗剂，IC50 为 7.2 nM，Ki 为 0.2 nM。
  3. GC15660 SB 399885 hydrochloride A 5-HT6 receptor antagonist
  4. GC12524 SB 699551 5-ht5a受体拮抗剂
  5. GC13583 CJ 033466 CJ 033466 是一种新型选择性 5-HT4 受体部分激动剂，EC50 为 9 nM，具有促胃动力作用。
  6. GC12657 LY 334370 hydrochloride A 5-HT1F receptor agonist
  7. GC10919 LY 272015 hydrochloride

    1-(3,4-二甲氧基苄基)-6-甲基-2,3,4,9-四氢-1H-吡啶并[3,4-B]吲哚盐酸盐

     A 5-HT2B receptor antagonist
  8. GC14607 1-Methylpsilocin 5-HT2C agonist,potent and selective
  9. GC14195 LP 12 hydrochloride LP 12 hydrochloride (compound 21) 是一种有效的选择性 5-HT7 受体激动剂，Ki 为 0.13 nM。
  10. GC17260 Ro 04-6790

    4-氨基-N-[2,6-双(甲基氨基)-4-嘧啶基]苯磺酰胺

     A 5-HT6 receptor antagonist
  11. GC16324 Nefazodone hydrochloride

    萘法唑酮盐酸盐,BMY-13754; MJ-13754-1

     A serotonin, norepinephrine, and dopamine reuptake inhibitor
  12. GC13109 Fananserin

    法南色林,RP 62203

     Fananserin (RP 62203) 是一种口服有效的选择性 5-hydroxytryptamine2 (5-HT2) 受体拮抗剂，对大鼠 5-HT2A 受体的 Ki 值为 0.37 nM。
  13. GC11308 L-703,664 succinate 5-HT1D receptor agonist
  14. GC11490 TCB-2 5-HT2A受体激动剂
  15. GC18112 LP 44 A selective 5-HT7 receptor agonist
  16. GC11929 Melperone hydrochloride

    1-[3-(对氟苯甲酰基)丙基]-4-甲基哌嗪氯化物

     An atypical antipsychotic
  17. GC16045 EMD 386088 hydrochloride EMD 386088 hydrochloride 是一种有效的血清素 6 受体 (5-HT6R) 激动剂。
  18. GC17714 PNU 22394 hydrochloride 5-HT2C agonist and partial 5-HT2A/5-HT2B agonist
  19. GC14583 R 59-022

    DKGI-I; Diacylglycerol kinase inhibitor I

    A DGK inhibitor
  20. GC12300 WAY 629 hydrochloride

    5-HT2C agonist
  21. GC17219 SDZ 205-557 hydrochloride 5-HT3/5-HT4 receptor antagonist
  22. GC17525 AS 19

    A 5-HT7 receptor agonist
  23. GC12383 SB 258585 hydrochloride A selective 5-HT6 receptor antagonist
  24. GC13883 Ritanserin

    利坦丝林,R 55667

     A potent 5-HT2A receptor antagonist
  25. GC15135 Ro 60-0175 fumarate A 5-HT2 receptor agonist
  26. GC14030 Altanserin hydrochloride 5-HT2A receptor antagonist
  27. GC11980 WAY 161503 hydrochloride A 5-HT2C receptor agonist
  28. GC17343 Zacopride hydrochloride

    查可必利盐酸盐

     Zacopride hydrochloride 是一种高效的 5-HT3 受体拮抗剂，对 5-HT3 和 5-HT4 受体的 Kis 分别为 0.38 和 373 nM。
  29. GC17706 R-96544 hydrochloride

    R-96544盐酸盐

     5-HT2 receptor antagonist
  30. GC10310 SB 206553 hydrochloride A 5-HT2C and 5-HT2B receptor antagonist
  31. GC15248 GR 125487 sulfamate 5-HT4 receptor antagonist
  32. GC14516 Mesulergine hydrochloride 5-HT2A and 2C receptor antagonist
  33. GC13607 LY 215840 5-HT2/5-HT7 receptor antagonist
  34. GC17140 GR 127935 hydrochloride A 5-HT1B and 5-HT1D receptor antagonist
  35. GC13298 NAS-181 NAS181 是一种有效的、选择性的大鼠 5-HT1B 受体拮抗剂，Ki 为 47 nM。
  36. GC16556 SB 221284 SB 221284 是一种选择性 5-HT2C/2B 受体拮抗剂，对 5-HT2A、5-HT2B 和 5-HT2C 受体的 pKi 值分别为 6.4、7.9 和 8.6。
  37. GC14347 SB 228357 SB 228357 是一种选择性、有效的口服活性 5-HT2C/2B 受体拮抗剂，5-HT2A、5-HT2B 和 5-HT2C 的 pKi 值分别为 6.9、8.0 和 9.0。
  38. GC12803 SB 204741 A 5-HT2B receptor antagonist
  39. GC11624 GR 113808 GR 113808是一种有效和选择性的5-HT4受体拮抗剂，pKb=8.8。
  40. GC16653 CP 94253 hydrochloride A 5-HT1B receptor agonist
  41. GC12735 SDZ SER 082 fumarate

    SDZSER082富马酸盐

     5-HT2B/2C receptor antagonist
  42. GC15551 SB 216641 hydrochloride A 5-HT1B receptor antagonist
  43. GC13438 SB 224289 hydrochloride

    SB-224289A

     A 5-HT1B receptor inverse agonist
  44. GC15630 SR 57227 hydrochloride

    SR57227盐酸盐

     A 5-HT3 receptor agonist
  45. GC11231 BW 723C86 hydrochloride

    BW723C86盐酸盐

     A selective HT2B receptor agonist
  46. GC17524 GR 55562 dihydrochloride 5-HT1B (5-HT1Dβ) silent antagonist
  47. GC10068 CP 93129 dihydrochloride A 5-HT1B receptor agonist
  48. GC15979 RS 16566 dihydrochloride (R)-zacopride 结合位点的配体
  49. GC16553 N-Desmethylclozapine

    N-去甲基氯氮平; Norclozapine; Desmethylclozapine; Normethylclozapine

     An active metabolite of clozapine
  50. GC14696 RS 67506 hydrochloride potent and selective 5-HT4 partial agonist
  51. GC15137 RS 56812 hydrochloride

    5-HT3 partial agonist

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