CCR(趋化因子受体)
CCR2 (C-C chemokine receptor type 2), the receptor for monocyte chemoattractant protein-1 (CCL2), mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase.
Products for CCR
- Cat.No. 产品名称 Information
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GC31330
CCX140
CCX140是一种有效的CCR2拮抗剂。
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GC30560
CCR2 antagonist 1
CCR2antagonist1是C-C趋化因子受体2型(CCR2)高亲和力、长时间作用的拮抗剂，其Ki值为2.4nM。
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GC19101
Cenicriviroc
An antagonist of CCR5 and CCR2
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GC19077
BMS-813160
A dual antagonist of CCR2 and CCR5
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GC18661
Vercirnon
An antagonist of CCR9
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GC14554
J 113863
J 113863 是一种有效的选择性 CCR1 (CD18) 拮抗剂，对人和小鼠 CCR1 受体的 IC50 值分别为 0.9 nM 和 5.8 nM。
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GC11946
SB 297006
A selective antagonist of CCR3
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GC17834
Teijin compound 1
A CCR2b antagonist
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GC11161
C 021 dihydrochloride
C 021 dihydrochloride 是一种有效的 CC 趋化因子受体 4 (CCR4) 拮抗剂。
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GC14519
BX 471
A selective CCR1 antagonist
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GC11026
RS 102895 hydrochloride
A chemokine receptor CCR2 antagonist
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GC11938
YM 022
YM 022 是一种高效、选择性和口服活性的胃泌素/胆囊收缩素 (CCK)-B 受体 (CCK-BR) 拮抗剂。
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GC17040
DAPTA
A CCR5 receptor antagonist
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GC12790
Pirfenidone
A pyridone derivative with antifibrotic activity
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GC13335
Bindarit
An inhibitor of MCP production
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GC15090
Maraviroc
马拉韦罗作为第一款CCR5拮抗剂已被批准用于治疗HIV感染，对hERG离子通道的IC50＞10μM。
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GC17421
Vicriviroc maleate
A CCR5 antagonist
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GC15489
RS 504393
A CCR2 chemokine receptor antagonist
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GC11636
MK-0812
A CCR2 antagonist
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GC11994
INCB8761(PF-4136309)
A CCR2 antagonist
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GC10207
INCB3344
An antagonist of CCR2
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GC14821
INCB 3284 dimesylate
An antagonist of the MCP-1 receptor CCR2
