Search Site
  • 0
    My Cart

    Click Here to Find How Many Items You Have Added:)

qq在线咨询
Home >> Signaling Pathways >> Neuroscience >> COX

COX(环氧合酶)

COX (cyclooxygenase) is an enzyme that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane.

Products for  COX

  1. Cat.No. 产品名称 Information
  2. GC47213 Diclofenac-d4 An internal standard for the quantification of diclofenac
  3. GC47212 Diclofenac amide A prodrug form of diclofenac
  4. GC47070 Celecoxib-d7 An internal standard for the quantification of celecoxib
  5. GC46781 Acetaminophen-d4 An internal standard for the quantification of acetaminophen
  6. GC46290 (±)-Ibuprofen-d3 An Analytical Reference Standard
  7. GC61371 Veratric acid Veratricacid(3,4-Dimethoxybenzoicacid)是从蔬菜和水果中得到的多酚物质，可口服，具有抗氧化、保护心血管和抗炎活性。当细胞受到UVB辐射时，Veratricacid能够减少上调的COX-2表达，降低PGE2和IL-6水平。
  8. GC61337 Tolmetin Tolmetin (Tolectin) is a nonsteroidal anti-inflammatory drug of the heterocyclic acetic acid derivative class and also exhibits analgesic and antipyretic activity.
  9. GC61238 Rehmapicrogenin Rehmapicrogenin可从Rehmanniaglutinosa的根部分离得到，通过抑制iNOS、COX-2和IL-6表现出有效的抗炎作用。
  10. GC61235 Regaloside B RegalosideB是一种从Liliumlongiflorum中分离出来的苯丙烷。RegalosideB可以抑制iNOS和COX-2的表达，具有抗炎活性。
  11. GC61234 Rebamipide D4 An internal standard for the quantification of rebamipide
  12. GC61193 Piroxicam D3 An internal standard for the quantification of piroxicam
  13. GC61180 Phenidone Phenidone (1-phenyl-3-pyrazolidinone), a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), is an organic compound that is primarily used as a photographic developer.
  14. GC61038 Mefenamic acid D4 An internal standard for the quantification of mefenamic acid
  15. GC60966 Ketorolac D5 An internal standard for the quantification of ketorolac
  16. GC60935 Indomethacin sodium hydrate A non-selective COX inhibitor
  17. GC60926 Ibuprofen impurity 1 Ibuprofenimpurity1是Ibuprofen的杂质。Ibuprofen是COX-1和COX-2的抑制剂，IC50值分别为13μM和370μM，具有抗炎的活性。
  18. GC60523 4-Methylamino antipyrine hydrochloride An active metabolite of metamizole
  19. GC60447 1-Hydroxy-ibuprofen 1-hydroxy Ibuprofen 是非甾体类抗炎药 (NSAID) 和非选择性 COX 抑制剂布洛芬的代谢物。
  20. GC60345 Sphondin Sphondin可从Heracleumlaciniatum中分离，对IL-1β诱导的A549细胞中COX-2蛋白和PGE2释放水平的升高具有抑制作用。
  21. GC60283 Pentagamavunon-1 Pentagamavunon-1 (PGV-1) 是Curcumin 的类似物，具有口服活性，通过多个机制诱导凋亡信号，如抑制COX-2 和 VEGF。Pentagamavunon-1 (PGV-1) 可抑制 NF-κB 的激活。
  22. GC60228 Loxoprofen sodium An NSAID and a prodrug form of loxoprofen-SRS
  23. GC60225 Licarin A LicarinA((+)-LicarinA)，可从多种植物中分离得到，显着降低二硝基苯肼-人血清白蛋白(DNP-HSA)刺激的RBL-2H3细胞。具有抗过敏作用。LicarinA降低TNF-α和PGD2产生，和COX-2表达。
  24. GC39583 Nimesulide D5 An internal standard for the quantification of nimesulide
  25. GC39534 Isoxicam Isoxicam 是一种口服有效的非甾体抗炎剂，可用于关节炎的研究。Isoxicam 是一种非选择性的 COX-1 和 COX-2 抑制剂。
  26. GC39307 4-Methylamino antipyrine An active metabolite of metamizole
  27. GC39134 Isofraxidin Isofraxidin (6,8-Dimethoxyumbelliferone), a bioactive coumarin compound isolated from the functional foods Siberian ginseng and Apium graveolens, is an anti-bacterial, anti-oxidant, and anti-inflammatory agent.
  28. GC39040 Taraxerol acetate Taraxerol acetate 是 COX-1 和 COX-2 抑制剂， IC50 值分别为 116.3 μM 和 94.7μM。Taraxerol acetate 具有抗癌作用并诱导细胞凋亡(apoptosis)。
  29. GC39013 FPL 62064 FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and prostaglandin synthetase (cyclooxygenase, COX) with IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and seminal vesicle prostaglandin synthetase, respectively. FPL 62064 has potent anti-inflammatory activity.
  30. GC45965 Tolfenamic Acid-d4 An internal standard for the quantification of tolfenamic acid
  31. GC45823 Rofecoxib-d5 An internal standard for the quantification of rofecoxib
  32. GC38678 Ethyl Caffeate Ethyl caffeate, a naturally occurring compound found in Bidens pilosa, suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2 and PGE2 in vitro.
  33. GC38616 Hamaudol Hamaudol 是从 Saposhnikovia divaricata 中分离出的一种色酮。Hamaudol 对环加氧酶 (COX)-1 和 COX-2 的活性具有明显的抑制能力，其 IC50 值分别为 0.30、0.57 mM，并且具有有效的镇痛和抗炎作用。
  34. GC38431 Dehydroevodiamine An alkaloid with diverse biological activities
  35. GC38224 Crocin II Crocin II (Crocin B, Crocetin gentiobiosylglucosyl ester, Tricrocin), a carotenoid chemical compound that is found in the flowers crocus and gardenia, is an antioxidant and neural protective agent.
  36. GC38198 Revaprazan hydrochloride Revaprazan Hydrochloride (YH1885) is a new reversible proton pump inhibitor with long-lasting acid-suppressive effects. Revaprazan Hydrochloride reversibly inhibits H(+)/K(+)-ATPase via binding to the K+-binding site of the pump.
  37. GC38184 Dehydrodiisoeugenol Dehydrodiisoeugenol, a naturally occurring lignan from Aristolochia taliscana (Aristolochiaceae), acts as a potent anti-inflammatory agent and shows various pharmacological activities, including anti-lipid peroxidation, anti-bacteial function, and hepatic drug metabolism enzyme inhibition.
  38. GC38151 Roburic acid Roburic acid 是秦艽中的四环三萜类化合物，作为一种 COX 的抑制剂，对 COX-1 和 COX-2 的 IC50 值分别为 5 和 9 μM。
  39. GC38066 Mavacoxib Mavacoxib (Trocoxil) is a selective, long-acting cyclooxygenase-2 (COX-2) inhibitor. Mavacoxib is a novel nonsteroidal anti-inflammatory drug (NSAID).
  40. GC45579 Tiaprofenic Acid A COX inhibitor and NSAID
  41. GC45278 (±)-Ketoprofen-d3 An internal standard for the quantification of (±)-ketoprofen
  42. GC36852 Parecoxib A prodrug form of valdecoxib
  43. GC36828 Oxaprozin D4 Oxaprozin D4是Oxaprozin的氘代化合物标准品。
  44. GC36747 Nitroaspirin Nitroaspirin (NCX 4016) 是一氧化氮 (NO) 供体和阿司匹林的硝基衍生物，Aspirin 与 Nitroaspirin 联合以抑制环加氧酶。Nitroaspirin (NCX 4016) 具有抗血栓形成和抗血小板特性，并作为 COX-1 的直接和不可逆抑制剂。Nitroaspirin (NCX 4016) 通过下调 EGFR/PI3K/STAT3 信号传导和调节 Bcl-2 家族蛋白，在顺铂耐药人卵巢癌细胞中引起细胞周期停滞和凋亡。
  45. GC36721 Nepafenac D5 An internal standard for the quantification of nepafenac
  46. GC36482 Loxoprofen An NSAID and a prodrug form of loxoprofen-SRS
  47. GC36314 Indobufen Indobufen (Ibustrin, K 3920) is a reversible platelet aggregation inhibitor. Indobufen is a reversible inhibitor of platelet cyclooxygenase (Cox) activity and suppresses thromboxane synthesis.
  48. GC36305 Imrecoxib Imrecoxib（BAP-909）艾瑞昔布是选择性环氧合酶 2 (COX-2) 抑制剂，IC50 值为 18 nM，也可以抑制 COX1 活性，IC50 值为 115 nM。Imrecoxib（BAP-909) 艾瑞昔布具有抗炎作用。
  49. GC36200 GW-406381 A NSAID and COX-2 inhibitor
  50. GC36014 Etoricoxib D4 Etoricoxib D4 (MK-0663 D4) 是 Etoricoxib 的氘代标记物。Etoricoxib 是一种非甾体抗炎剂，为可口服的、选择性的 COX-2 抑制剂，对人全血 COX-2 和 COX-1 的 IC50 值分别为 1.1 μM 和 116 μM。
  51. GC35493 Benzoylgomisin O Benzoylgomisin O 是从 Schisandra rubriflora 中分离的化合物，对 15-LOX、COX-1、COX-2 酶有抑制作用，且具有抗炎活性。

Items 51 to 100 of 279 total

per page
  2. 1
  3. 2
  4. 3
  5. 4
  6. 5

Set Descending Direction