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COX(环氧合酶)

COX (cyclooxygenase) is an enzyme that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane.

Products for  COX

  1. Cat.No. 产品名称 Information
  2. GC35013 [8]-Shogaol [8]-Shogaol,生姜中的一种刺激性酚类化合物,具有抗血小板活性 (IC50=5 μM) 和抑制 COX-2 (IC50=17.5 μM)。[8]-Shogaol 诱导人白血病细胞凋亡。
  3. GC35012 [10]-Shogaol A phenol with diverse biological activities
  4. GC44597 Peonidin (chloride) A plant pigment with antioxidant properties
  5. GC44439 NO-Indomethacin An NSAID-NO donor hybrid with anti-cancer activity
  6. GC44167 Metamizole (sodium salt) A nonopioid prodrug
  7. GC43635 Ethyl p-methoxycinnamate A natural product with diverse actions
  8. GC43447 Diclofenac methyl ester A prodrug form of diclofenac
  9. GC43149 CAY10404 A COX-2 inhibitor
  10. GC42859 Aspirin-d4 An internal standard for the quantification of aspirin
  11. GC42692 Aceclofenac methyl ester A potential impurity in commercial preparations of aceclofenac
  12. GC42691 Aceclofenac ethyl ester A potential impurity found in commercial preparations of aceclofenac
  13. GC42201 3,3'-Diiodo-L-thyronine A metabolite of thyroid hormone
  14. GC41761 1-(6-Methoxy-2-naphthyl)ethanol A potential impurity found in commercial naproxen preparations
  15. GC41658 (±)-2-hydroxy Ibuprofen A metabolite of ibuprofen
  16. GC41645 Jacaric Acid A conjugated PUFA
  17. GC41634 Metyrosine An inhibitor of tyrosine hydroxylase
  18. GC41623 β-Elemonic Acid A triterpene with anticancer activity
  19. GC41396 Heneicosapentaenoic Acid A 21:5 ω-3 fatty acid
  20. GC41389 (S)-Ketorolac A non-selective COX inhibitor
  21. GC41218 Guaiacol Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin.
  22. GC40842 (-)-Catechin A diastereoisomer of catechin
  23. GC40686 N-trans-Feruloyltyramine A phenolic amide with diverse biological activities
  24. GC40651 Oxyphenbutazone An NSAID
  25. GC40565 Feprazone A COX-2 inhibitor
  26. GC40352 Cafestol A natural diterpene which increases serum cholesterol
  27. GC40262 α-Humulene A sesquiterpene with diverse biological activities
  28. GC40227 Indomethacin-d4 An internal standard for the quantification of indomethacin
  29. GC40065 Meloxicam-d3 An internal standard for the quantification of meloxicam
  30. GC34116 Hexahydrocurcumin A natural product and an active metabolite of curcumin
  31. GC34028 Nitroflurbiprofen (HCT 1206) Nitroflurbiprofen (HCT 1206) 是一种环氧合酶 (COX) 抑制剂,具有提供一氧化氮 (NO) 的特性,可调节门脉高压性肝硬化大鼠肝内血管张力的增加。
  32. GC33893 FR-188582 FR-188582是高选择性的环氧合酶(COX-2)抑制剂,IC50值为17nM。
  33. GC33876 Propyphenazone (4-Isopropylantipyrine) Propyphenazone(4-Isopropylantipyrine, Isopropyrine), an analgesic and antipyretic agent, is a selective cyclooxygenase-2 inhibitor with anti-inflammatory activity.
  34. GC33861 Inulicin (1-O-Acetylbritannilactone) A sesquiterpene lactone with diverse biological activities
  35. GC33632 Veratric acid (3,4-Dimethoxybenzoic acid) Veratric acid (3,4-Dimethoxybenzoic acid), a simple benzoic acid derived from plants and fruits, has anti-oxidant, anti-inflammation, and blood pressure-lowering effects. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation.
  36. GC33484 Ampyrone (4-Aminoantipyrine) 4-Aminoantipyrine(Ampyrone) is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. It is used as a reagent for biochemical reactions producing peroxides or phenols.
  37. GC32957 (-)-Catechin gallate ((-)-Catechin 3-gallate) A polyphenol with diverse biological activities
  38. GC32841 Catechin ((+)-Catechin) (+)-Catechin (Cianidanol, Catechinic acid, Catechuic acid) is an antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
  39. GC32640 Pamicogrel (KBT3022) A COX inhibitor and an antiplatelet agent
  40. GC32030 COX2-IN-1 COX2-IN-1是选择性的,诱导型的COX2抑制剂,IC50值为0.24μM。COX2-IN-1是具有抗炎和止痛活性的抗炎物。
  41. GC32026 Naproxen etemesil (LT-NS 001) Naproxen etemesil (LT-NS 001) 是一种亲脂性、非酸性、无活性的萘普生前药,一旦被吸收就会水解成具有药理活性的萘普生。
  42. GC31985 SC58451 SC58451是一个强效的,有选择性的COX-2抑制剂。
  43. GC31967 COX/5-LO-IN-1 COX/5-LO-IN-1是cylooxygenase和5-lipoxygenase的抑制剂,用于炎症性和过敏性疾病的研究。
  44. GC31965 Timegadine (SR1368) Timegadine (SR1368) 是一种新型抗炎剂,被发现是一种有效的、竞争性的环加氧酶 (COX) 和脂加氧酶抑制剂,IC50 范围为 5 nM(洗涤过的兔血小板)至 20 μM(大鼠脑) ) 用于 COX 和 100 μ;M 用于马血小板匀浆的胞质溶胶部分和洗涤过的兔血小板中的脂加氧酶。
  45. GC31962 COX-2-IN-1

    COX-2-IN-1是一个强效的COX-2抑制剂,其IC50值为3.9μM。

  46. GC31960 SC57666

    SC57666是选择性的COX2抑制剂,IC50值为26nM。

  47. GC31956 Tilmacoxib (JTE522) Tilmacoxib (JTE522) (JTE522) 是一种高度选择性、时间依赖性和不可逆的人 COX-2 抑制剂,在酶试验中 IC50 为 85 nM。
  48. GC31943 Methyl Salicylate (Wintergreen oil) Methyl salicylate (Betula oil, Gaultheria oil, Methyl 2-hydroxybenzoate, Natural wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. It is an agonist for TRPA1 and TRPV1.
  49. GC31835 S-2474 S-2474是COX-2和5-lipoxygenase的抑制剂,在人完整的细胞中,对COX-2和COX-1的IC50值分别为11nM和27μM,为一种非甾体抗炎药。
  50. GC31826 Thioflosulide (L-745337) Thioflosulide (L-745337) (L-745337) 是一种选择性 cyclooxygenase-2 (COX2) 抑制剂,IC50 为 2.3 nM,具有抗炎活性。
  51. GC31818 Flosulide (ZK 38997) Flosulide (ZK 38997) 是一种有效的选择性 COX-2 抑制剂,用于治疗炎症性疾病。

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